Human artificial chromosomes: Potential applications and clinical considerations

被引：22

作者：

Basu, Joydeep ^{[1
]}

Willard, Huntington F. ^{[1
]}

机构：

[1] Duke Univ, Inst Genome Sci & Policy, Durham, NC 27708 USA

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2006年 / 53卷 / 05期

关键词：

D O I：

10.1016/j.pcl.2006.08.013

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Human artificial chromosomes demonstrate promise as a novel class of nonintegrative gene therapy vectors. The authors outline current developments in human artificial chromosome technology and examine their potential for clinical application.

引用

页码：843 / +

页数：12

共 50 条

[21] Human Artificial Chromosomes and Their Transfer to Target Cells
Ponomartsev, S. V.
Sinenko, S. A.
Tomilin, A. N.
[J]. ACTA NATURAE, 2022, 14 (03): : 35 - 45
[22] Artificial human chromosomes created for the first time
Josefson, D
[J]. BRITISH MEDICAL JOURNAL, 1997, 314 (7087): : 1070 - 1070
[23] Human Artificial Chromosomes that Bypass Centromeric DNA
Logsdon, Glennis A.
Gambogi, Craig W.
Liskovykh, Mikhail A.
Barrey, Evelyne J.
Larionov, Vladimir
Miga, Karen H.
Heun, Patrick
Black, Ben E.
[J]. CELL, 2019, 178 (03) : 624 - +
[24] Human artificial chromosomes - Providing a little stability
Warburton, PE
Kipling, D
[J]. NATURE, 1997, 386 (6625) : 553 - 555
[25] Impact and implications of yeast and human artificial chromosomes
Schlessinger, D
[J]. INTERNATIONAL SEMINAR ON NUCLEAR WAR AND PLANETARY EMERGENCIES - 22ND SESSION: NUCLEAR SUBMARINE DECONTAMINATION, CHEMICAL STOCKPILED WEAPONS, NEW EPIDEMICS, CLONING OF GENES, NEW MILITARY THREATS, GLOBAL PLANETARY CHANGES: OZONE HOLE & CLIMATE IMPACT, DESERTIFICATION, WATER, FORESTRY & URBANISM, AND COSMIC OBJECTS & ENERGY, 1998, : 99 - 107
[26] Genetics - Common diseases and human artificial chromosomes
Swift, M
Shapiro, LR
[J]. LANCET, 1997, 350 : SIII8 - SIII8
[27] Segregation of natural and artificial human chromosomes.
Rudd, MK
Willard, HF
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (04) : 217 - 217
[28] Neocentromeres and human artificial chromosomes: An unnatural act
Willard, HF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (10) : 5374 - 5376
[29] Potential Applications of Artificial Intelligence in Clinical Trials for Alzheimer's Disease
Seo, Younghoon
Jang, Hyemin
Lee, Hyejoo
[J]. LIFE-BASEL, 2022, 12 (02):
[30] The Potential of Human Artificial Chromosomes in Biomedicine-are they the ultimate vector for gene therapy treatments in the clinic?
Bridger, Joanna M.
[J]. CHROMOSOME RESEARCH, 2015, 23 (02) : 352 - 353

← 1 2 3 4 5 →