The management of adult aggressive non-Hodgkin's lymphomas

被引：12
|
作者：
Couderc, B
Dujols, JP
Mokhtari, F
Norkowski, JL
Slawinski, JC
Schlaifer, D
机构：
[1] Grp Radiotherapie & Oncol Med Pyrennes, GROP, F-65000 Tarbes, France
[2] Grp Radiotherapie & Oncol Med Pyrenees, GROP, F-64000 Pau, France
来源：
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2000年 / 35卷 / 01期
关键词：
lymphoma; non-Hodgkin's; high-grade; radiotherapy; chemotherapy; review;
D O I：
10.1016/S1040-8428(99)00037-2
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Aggressive non-Hodgkin's lymphoma include diffuse large B-cell lymphoma, anaplastic large cell lymphoma, and different peripheral T-cell lymphomas. An international prognostic index has been developed including age, serum LDH, performance status, and extranodal involvement. For localized aggressive lymphoma, the preferred treatment is 3-4 CHOP and radiation therapy, with a cure rate of 70-80%. For disseminated aggressive lymphoma, current regimens have a cure rate of less than 40%. Innovative strategies, including dose escalation, autologus stem cell support, new drugs, and immunotherapy are being explored to improve these results. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：33 / 48
页数：16
相关论文
共 50 条
  • [31] VB-CHEP chemotherapy regimen for aggressive non-Hodgkin's lymphomas
    Yalcin, S
    Kars, A
    Ozisik, Y
    Tekuzman, G
    Özyilkan, Ö
    Celik, I
    Barista, I
    Güllü, I
    Güler, N
    Baltali, E
    Firat, D
    [J]. EUROPEAN JOURNAL OF HAEMATOLOGY, 1998, 61 (04) : 261 - 265
  • [32] Classification of non-Hodgkin's lymphomas
    Norton, AJ
    [J]. BAILLIERES CLINICAL HAEMATOLOGY, 1996, 9 (04): : 641 - 652
  • [33] Progress in the non-Hodgkin's lymphomas
    Yuen, AR
    [J]. ANNALS OF ONCOLOGY, 1999, 10 : 19 - 22
  • [34] Radioimmunotherapy of non-Hodgkin's lymphomas
    Cheson, Bruce D.
    [J]. CURRENT DRUG TARGETS, 2006, 7 (10) : 1293 - 1300
  • [35] Non-Hodgkin's lymphomas - Preface
    Linch, DC
    [J]. BAILLIERES CLINICAL HAEMATOLOGY, 1996, 9 (04): : R9 - R9
  • [36] Non-Hodgkin's lymphomas (NHL)
    Gustafsson, A
    [J]. ACTA ONCOLOGICA, 1996, 35 (07) : 102 - 116
  • [37] Non-Hodgkin's lymphomas in breast
    Gursan, N.
    Ozmen, S.
    Sener, E.
    [J]. VIRCHOWS ARCHIV, 2015, 467 : S61 - S61
  • [38] Epratuzumab in non-Hodgkin's lymphomas
    Furman R.R.
    Coleman M.
    Leonard J.P.
    [J]. Current Treatment Options in Oncology, 2004, 5 (4) : 283 - 288
  • [39] Radiotherapy in non-Hodgkin's lymphomas
    Gospodarowicz, M.
    [J]. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2012, 82 : S5 - S6
  • [40] Non-Hodgkin's lymphomas of the colon
    Bairey, Osnat
    Ruchlemer, Rosa
    Shpilberg, Ofer
    [J]. ISRAEL MEDICAL ASSOCIATION JOURNAL, 2006, 8 (12): : 832 - 835
12345