Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola

被引：19
|
作者：
Zhao, Dong-Lin [1 ]
Shao, Chang-Lun [1 ]
Wang, Chao-Yi [1 ]
Wang, Mei [1 ]
Yang, Lu-Jia [1 ]
Wang, Chang-Yun [1 ,2 ]
机构：
[1] Ocean Univ China, Sch Med & Pharm, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
[2] Ocean Univ China, Inst Evolut & Marine Biodivers, Qingdao 266003, Peoples R China
来源：
MOLECULES | 2016年 / 21卷 / 02期
基金：
中国国家自然科学基金;
关键词：
sponge-derived fungus; Corynespora cassiicola; naphthalenone; depsidone; cytotoxicity; NATURAL-PRODUCTS; DERIVATIVES; SUBSTANCES; GROWTH; ASSAY;
D O I：
10.3390/molecules21020160
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived fungus Corynespora cassiicola XS-20090I7. Their structures including absolute configurations were determined by spectroscopic data and electronic circular dichroism (ECD) spectra. Compounds 4 and 5 showed cytotoxicity against human promyelocytic leukemia HL-60 and human cervical carcinoma HeLa cell lines.
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页数：6
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