Mixed steatohepatitis: more questions than answers (Part 1)

被引:1
|
作者
Raikhelson, K. L. [1 ]
Kondrashina, E. A. [1 ]
Pazenko, E., V [1 ]
机构
[1] St Petersburg State Univ, Sci Clin & Educ Ctr Gastroenterol & Hepatol, St Petersburg, Russia
关键词
steatohepatitis; non-alcoholic fatty liver disease; drug-induced liver injury; alcoholic liver disease; ademetionine; NONALCOHOLIC FATTY LIVER; MODEST ALCOHOL-CONSUMPTION; S-ADENOSYLMETHIONINE; HEPATOCELLULAR-CARCINOMA; DECREASED PREVALENCE; HEPATIC STEATOSIS; RISK-FACTORS; VITAMIN-E; DISEASE; FIBROSIS;
D O I
10.26442/00403660.2020.12.200470
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The term "steatohepatitis" is used for a heterogeneous group of diseases of various etiologies, characterized by a similar morphological picture. Earlier the diagnosis of non-alcoholic fatty liver disease implied the exclusion of other causes of steatohepatitis, in recent years it has been suggested that a combination of various etiological variants of steatohepatitis is possible. The review considers the terminological, epidemiological and pathogenetic aspects of the most common combination: metabolic and alcoholic genesis, the issues of the mutual influence of etiopathogenetic factors and the identification of the predominant process. Issues of existing and prospective pathogenetic and symptomatic therapy are discussed in detail. Treatment of steatohepatitis is based on the elimination of known causal factors and lifestyle modification; therapy includes medications, that have been proven to be effective in certain types of steatohepatitis and symptomatic therapy as well.
引用
收藏
页码:91 / 96
页数:6
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