Microbiome and Gut Inflammation

被引:12
|
作者
Autenrieth, Daniel M. [3 ]
Baumgart, Daniel C. [1 ,2 ]
机构
[1] Charite Univ Med Berlin, Interdisziplinare Forsch & Behandlungszentrum, Med Klin Schwerpunkt Gastroenterol & Hepatol, Berlin, Germany
[2] Berlin Inst Hlth BIH, Berlin, Germany
[3] Charite Univ Med Berlin, Med Klin Schwerpunkt Gastroenterol & Hepatol, Berlin, Germany
关键词
Microbiome; microbiota; inflammation; inflammatory bowel diseases; ulcerative colitis; Crohn's disease; Clostridium difficile; RECURRENT CLOSTRIDIUM-DIFFICILE; ULCERATIVE-COLITIS; FECAL MICROBIOTA; ESCHERICHIA-COLI; BOWEL DISEASES; HEALTH; TRANSPLANTATION; GASTROENTEROLOGY; MESALAZINE; ANTIBODIES;
D O I
10.1055/s-0042-111608
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In the past decade the gut microbiome has received scientific attention like few other topics. It has become increasingly apparent that the commensal microbiota plays an important role in maintaining the health of the host. Changes of the microbiota composition or function coincide with different disorders such as infectious (i.e. Clostridium difficile infection) or inflammatory bowel diseases like Crohn's disease or ulcerative colitis. Although the significance of this observation has not yet been fully elucidated and understood, several of attempts aimed atmodulating the microbiota composition have been made. This article gives an update on current advances and clinical implications of the gut microbiome in infectious and inflammatory bowel diseases.
引用
收藏
页码:261 / 266
页数:6
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