A natural inhibitor of c-Met that sensitizes head and neck cancer cells resistant to EGFR and PI3K co-targeting

被引：0
|
作者：
Anisuzzaman, Asm [1 ]
Hague, Abedul [2 ]
Butler, Brian [3 ]
Amin, Arm R. [3 ]
机构：
[1] Emory Univ, Atlanta, GA 30322 USA
[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[3] Marshall Univ, Huntington, WV USA
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-706
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
706
引用
收藏
页数：2
相关论文
共 50 条
  • [21] The influence of PI3K inhibition on the radiotherapy response of head and neck cancer cells
    Mary Glorieux
    Rüveyda Dok
    Sandra Nuyts
    Scientific Reports, 10
  • [22] Elevated Insulin Can Reduce Effectiveness of PI3K Inhibitors - Rationale for Co-targeting the Insulin Receptor Family and PI3K
    Blouin, M. J.
    Zhao, Y.
    Birman, E.
    Pollak, M.
    EUROPEAN JOURNAL OF CANCER, 2012, 48 : S151 - S151
  • [23] Immunoprofile of c-MET/PI3K signaling in human salivary gland tumors
    Vasconcelos, Artur Cunha
    Wagner, Vivian Petersen
    Meurer, Luise
    Vargas, Pablo Agustin
    de Souza, Lelia Batista
    Fonseca, Felipe Paiva
    Squarize, Cristiane Helena
    Castilho, Rogerio Moraes
    Martins, Manoela Domingues
    ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 2015, 120 (02): : 238 - 247
  • [24] Synthetic lethality by co-targeting mitochondrial apoptosis and PI3K/Akt/mTOR signaling
    Fulda, Simone
    MITOCHONDRION, 2014, 19 : 85 - 87
  • [25] Dual Blockade of EGFR and c-Met Abrogates Redundant Signaling and Proliferation in Head and Neck Carcinoma Cells
    Xu, Hai
    Stabile, Laura P.
    Gubish, Christopher T.
    Gooding, William E.
    Grandis, Jennifer R.
    Siegfried, Jill M.
    CLINICAL CANCER RESEARCH, 2011, 17 (13) : 4425 - 4438
  • [26] Activation of the EGFR/PI3K/AKT pathway limits the efficacy of trametinib treatment in head and neck cancer
    Novoplansky, Ofra
    Shnerb, Avital B.
    Marripati, Divyasree
    Jagadeeshan, Sankar
    Abu Shareb, Raghda
    Conde-Lopez, Cristina
    Zorea, Jonathan
    Prasad, Manu
    Ben Lulu, Talal
    Yegodayev, Ksenia M.
    Benafsha, Chen
    Li, Yushi
    Kong, Dexin
    Kuo, Fengshen
    Morris, Luc G. T.
    Kurth, Ina
    Hess, Jochen
    Elkabets, Moshe
    MOLECULAR ONCOLOGY, 2023, : 2618 - 2636
  • [27] Co-targeting c-Met and c-Src pathways to inhibit metastatic cancer cell migration and invasion.
    Dai, Yao
    Siemann, Dietmar W.
    CANCER RESEARCH, 2021, 81 (13)
  • [28] c-Met activation mediates resistance to Src inhibition in head and neck cancer cells
    Saigal, Babita
    Sen, Banibrata
    Johnson, Faye
    CANCER RESEARCH, 2009, 69
  • [29] Inhibition of c-Met activation sensitizes osteosarcoma cells to cisplatin via suppression of the PI3K-Akt signaling
    Wang, Kelai
    Zhuang, Yan
    Liu, Chunlan
    Li, Yang
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2012, 526 (01) : 38 - 43
  • [30] Co-targeting asparagine and glutamine metabolism is a viable treatment strategy for PI3K/PTEN mutated cervical cancer
    Gabriel, Nishanth Noel
    Muhammad, Naoshad
    Cho, Kevin
    Jayachandran, Kay
    Zhang, Jin
    Patti, Gary
    Schwarz, Julie
    CANCER RESEARCH, 2024, 84 (06)
12345