Group A Streptococcal Toxic Shock Syndrome After Uterine Instrumentation

A case report of intrauterine group A streptococcal (GAS) infection following an endometrial pipelle biopsy complicated by toxic shock syndrome (TSS). Our aim is to elicit the awareness of the possibility of acquiring GAS as a cause of Endometritis that can be complicated by toxic shock syndrome. GAS infection is a possible cause of endometritis with the risk of invasive disease that can lead TSS, which carries a high mortality. A case report of a 65 years old woman who developed isolated GAS following endometrial pipelle biopsy for postmenopausal bleeding (PMB). The patient developed TSS that warranted admission to the ITU for management of toxemia and correction of the electrolyte imbalance. A literature review of the reported cases of GAS pelvic infection concluded that invasive disease could occur in adult women with a rapidly progressive course with high mortality rates.