Direct difunctionalization of activated alkynes via domino oxidative benzylation/1,4-aryl migration/decarboxylation reactions under metal-free conditions

被引：34
|
作者：
Miao, Tao [1 ]
Xia, Dong [1 ]
Li, Yang [1 ]
Li, Pinhua [1 ]
Wang, Lei [1 ,2 ]
机构：
[1] Huaibei Normal Univ, Dept Chem, Huaibei 235000, Anhui, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 15期
基金：
美国国家科学基金会;
关键词：
C-H BONDS; DEHYDROGENATIVE COUPLING CDC; CARBON-HYDROGEN; RADICAL CYCLIZATION; ALKYNOATES; FUNCTIONALIZATION; C(SP(3))-H; COUMARINS; TOLUENE; ACIDS;
D O I：
10.1039/c5cc10084d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The oxidative difunctionalization of aryl alkynoates via benzyl radical initiated intramolecular 1,4-arylmigration and decarboxylation tandem process was developed in the presence of tert-butyl hydroperoxide as an oxidant, which provides a direct and selective route to a variety of trisubstituted alkenes from simple toluene derivatives and aryl alkynoates.
引用
收藏
页码：3175 / 3178
页数：4
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