Role of atrial substrate and spatiotemporal organization in atrial fibrillation

被引：9

作者：

Kim, Albert M. ^{[1
]}

Olgin, Jeffrey E. ^{[1
]}

Everett, Thomas H. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Cardiac Electrophysiol Sect, Dept Med, San Francisco, CA 94143 USA

来源：

HEART RHYTHM | 2009年 / 6卷 / 08期

关键词：

Atrial fibrillation; Spatiotemporal organization; Animal models; Dominant frequency; Optical mapping; PULMONARY VEIN ISOLATION; CANINE MODEL; DOMINANT FREQUENCY; HEART-FAILURE; SPATIAL-ORGANIZATION; ACTIVATION; TACHYCARDIA; CONDUCTION; DOGS; MECHANISMS;

D O I：

10.1016/j.hrthm.2009.02.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation (AF) is a heterogeneous disease that presents in a wide range of clinical scenarios. Correspondingly, a diverse array of large animal models has developed for the study of AF. Different atrial substrate exists in these models, and quantitative analysis of the AF that develops in each case reveals unique characteristics. This article reviews the defining properties of several prominent AF animal models, with a focus on how spatiotemporal organization can discriminate between AF substrates. It addresses how spatiotemporal assessments have been extended to human AF and discusses the insights gained from these new analyses.

引用

页码：S1 / S7

页数：7

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