AMG 510, a novel small molecule inhibitor of KRAS(G12C), for patients (pts) with advanced gastrointestinal (GI) cancers: Results from the CodeBreaK100 phase I trial

被引:4
|
作者
Strickler, J. H. [1 ]
Fakih, M. [2 ]
Price, T. J. [3 ]
Desai, J. [4 ]
Durm, G. [5 ]
Krauss, J. C. [6 ]
Kuboki, Y. [7 ]
Kim, T. W. [8 ]
Sacher, A. [9 ]
Henary, H. [10 ]
Kim, J. [11 ]
Hong, D. S. [12 ]
机构
[1] Duke Canc Ctr, Med, Durham, NC USA
[2] City Hope Natl Med Ctr, Med Oncol & Therapeut Res, Duarte, CA USA
[3] Queen Elizabeth Hosp, Emergency Dept, Med Oncol, Woodville, SA, Australia
[4] Peter MacCallum Canc Ctr, Med Oncol, Melbourne, Vic, Australia
[5] Dept Med, Div Hematol Oncol, Indianapolis, IN USA
[6] Univ Michigan, Div Hematol Oncol, Ann Arbor, MI 48109 USA
[7] Canc Inst Hosp JFCR, Dept Expt Therapeut & GI Oncol, Tokyo, Japan
[8] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Oncol, Seoul, South Korea
[9] Princess Margaret Canc Ctr, Med Oncol & Hematol Dept, Toronto, ON, Canada
[10] Amgen Inc, Early Dev Oncol Dept, Thousand Oaks, CA USA
[11] Amgen Inc, Biostat, Thousand Oaks, CA USA
[12] Univ Texas MD Anderson Canc Ctr, Invest Canc Therapeuitcs Dept, Houston, TX 77030 USA
关键词
D O I
10.1016/j.annonc.2020.10.103
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
83MO
引用
收藏
页码:S1274 / S1275
页数:2
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