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- [1] AMG 510, a novel small molecule inhibitor of KRAS G12C, for patients with advanced gastrointestinal cancers: Results from the CodeBreak 100 phase 1 trialANNALS OF ONCOLOGY, 2020, 31 : S226 - S226Strickler, J.论文数: 0 引用数: 0 h-index: 0机构: Duke Univ, Med Ctr, Durham, NC 27706 USA Duke Univ, Med Ctr, Durham, NC 27706 USAFakih, M.论文数: 0 引用数: 0 h-index: 0机构: City Hope Comprehens Canc Ctr, Dept Med Oncol & Therapeut Res, Duarte, CA USA Duke Univ, Med Ctr, Durham, NC 27706 USAPrice, T.论文数: 0 引用数: 0 h-index: 0机构: Univ Adelaide, Queen Elizabeth Hosp, Adelaide, SA, Australia Duke Univ, Med Ctr, Durham, NC 27706 USADesai, J.论文数: 0 引用数: 0 h-index: 0机构: Royal Melbourne Hosp, Peter MacCallum Canc Ctr, Victoria, BC, Canada Duke Univ, Med Ctr, Durham, NC 27706 USADurm, G.论文数: 0 引用数: 0 h-index: 0机构: Indiana Univ Sch Med, Indianapolis, IN 46202 USA Duke Univ, Med Ctr, Durham, NC 27706 USA论文数: 引用数: h-index:机构:Kuboki, Y.论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr East, Kashiwa, Chiba, Japan Duke Univ, Med Ctr, Durham, NC 27706 USAKim, T.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulsan, Asan Med Ctr, Seoul, South Korea Duke Univ, Med Ctr, Durham, NC 27706 USASacher, A.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Toronto, ON, Canada Duke Univ, Med Ctr, Durham, NC 27706 USAHenary, H.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Thousand Oaks, CA USA Duke Univ, Med Ctr, Durham, NC 27706 USAKim, J.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Biostat, Thousand Oaks, CA 91320 USA Duke Univ, Med Ctr, Durham, NC 27706 USAHong, D.论文数: 0 引用数: 0 h-index: 0机构: UT MD Anderson Canc Ctr, Houston, TX USA Duke Univ, Med Ctr, Durham, NC 27706 USA
- [2] CodeBreak 100: Activity of AMG 510, a novel small molecule inhibitor of KRASG12C, in patients with advanced colorectal cancer.JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)Fakih, Marwan论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USADesai, Jayesh论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAKuboki, Yasutoshi论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAStrickler, John H.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAPrice, Timothy Jay论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USADurm, Greg Andrew论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAFalchook, Gerald Steven论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USADenlinger, Crystal S.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAKrauss, John C.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAShapiro, Geoffrey论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAKim, Tae Won论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAPark, Keunchil论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USACoveler, Andrew L.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAMunster, Pamela N.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USALi, Bob T.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAKim, June论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAHenary, Haby Adel论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USANgarmchamnanrith, Gataree论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAHong, David S.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA
- [3] Phase I study of AMG 510, a novel molecule targeting KRAS G12C mutant solid tumoursANNALS OF ONCOLOGY, 2019, 30 : 163 - +Govindan, R.论文数: 0 引用数: 0 h-index: 0机构: Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAFakih, M. G.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, Dept GI Med Oncol, 1500 E Duarte Rd, Duarte, CA 91010 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAPrice, T. J.论文数: 0 引用数: 0 h-index: 0机构: Queen Elizabeth Hosp, Dept Med Oncol, Woodville, SA, Australia Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAFalchook, G. S.论文数: 0 引用数: 0 h-index: 0机构: HealthONE, Sarah Cannon Res Inst, Denver, CO USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USADesai, J.论文数: 0 引用数: 0 h-index: 0机构: Peter MacCallum Canc Ctr, Dept Med Oncol, Melbourne, Vic, Australia Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAKuo, J. C.论文数: 0 引用数: 0 h-index: 0机构: Scientia Clin Res Ltd, Dept Med Oncol, Randwick, NSW, Australia Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAStrickler, J. H.论文数: 0 引用数: 0 h-index: 0机构: Duke Univ, Med Ctr, Dept Med, Div Med Oncol, Durham, NC 27710 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAKrauss, J. C.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Div Hematol Oncol, Internal Med, Ann Arbor, MI 48109 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USALi, B. T.论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USADenlinger, C. S.论文数: 0 引用数: 0 h-index: 0机构: Fox Chase Canc Ctr, Dept Hematol Oncol, 7701 Burholme Ave, Philadelphia, PA 19111 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USADurm, G.论文数: 0 引用数: 0 h-index: 0机构: Indiana Univ, Dept Hematol Oncol, Simon Canc Ctr, Indianapolis, IN 46204 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USANgang, J.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Global Dev, Thousand Oaks, CA 91320 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAHenary, H.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Global Dev, Thousand Oaks, CA 91320 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USANgarmchamnanrith, G.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Global Dev, Thousand Oaks, CA 91320 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USARasmussen, E.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Global Biostat, Thousand Oaks, CA 91320 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAMorrow, P. K.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Global Dev, Thousand Oaks, CA 91320 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USAHong, D. S.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Invest Canc Therapeut, Houston, TX 77030 USA Washington Univ, Sch Med, Dept Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO USA
- [4] CodeBreak 200: A phase III multicenter study of sotorasib (AMG 510), a KRAS(G12C) inhibitor, versus docetaxel in patients with previously treated advanced non-small cell lung cancer (NSCLC) harboring KRAS p.G12C mutationANNALS OF ONCOLOGY, 2020, 31 : S894 - S895Reck, M.论文数: 0 引用数: 0 h-index: 0机构: German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, Germany German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanySpira, A.论文数: 0 引用数: 0 h-index: 0机构: Virginia Canc Specialists PC, Fairfax, VA USA US Oncol Res, The Woodlands, TX USA German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyBesse, B.论文数: 0 引用数: 0 h-index: 0机构: Inst Gustave Roussy, Dept Canc Med, Villejuif, France German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyWolf, J.论文数: 0 引用数: 0 h-index: 0机构: Univ Klinikum Koln, Dept Internal Med, Cologne, Germany German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanySkoulidis, F.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Thorac & Head & Neck Med Oncol, Houston, TX 77030 USA German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyBorghaei, H.论文数: 0 引用数: 0 h-index: 0机构: Fox Chase Canc Ctr, Dept Hematol Oncol, 7701 Burholme Ave, Philadelphia, PA 19111 USA German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyGoto, K.论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr Hosp East, Dept Thorac Oncol, Kashiwa, Chiba, Japan German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, Germany论文数: 引用数: h-index:机构:Griesinger, F.论文数: 0 引用数: 0 h-index: 0机构: Carl von Ossietzky Univ Oldenburg, Univ Dept Internal Med Oncol, Pius Hosp, Oldenburg, Germany German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyFelip, E.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ Hosp, Thorac Oncol & H&N Canc Unit, Dept Med Oncol, Barcelona, Spain German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyBoyer, M.论文数: 0 引用数: 0 h-index: 0机构: Chris OBrien Lifehouse, Dept Med Oncol, Camperdown, NSW, Australia German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyBarrios, C. H.论文数: 0 引用数: 0 h-index: 0机构: Pontificia Univ Catolica Rio Grande do Sul, Oncol Res Ctr, Hosp Sao Lucas, Porto Alegre, RS, Brazil German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyGoss, G.论文数: 0 引用数: 0 h-index: 0机构: Ottawa Hosp Res Inst, Dept Internal Med, Ottawa, ON, Canada German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyYang, H.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Biostat, Thousand Oaks, CA 91320 USA German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyObiozor, C.论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Clin Dev, Thousand Oaks, CA 91320 USA German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, GermanyRamalingam, S. S.论文数: 0 引用数: 0 h-index: 0机构: Emory Univ, Dept Hematol & Med Oncol, Sch Med, Atlanta, GA USA German Ctr Lung Res, LungenClin, Airway Res Ctr North, Grosshansdorf, Germany
- [5] CodeBreak 100: Phase I study of AMG 510, a novel KRASG12C inhibitor, in patients (pts) with advanced solid tumors other than non-small cell lung cancer (NSCLC) and colorectal cancer (CRC).JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)Hong, David S.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USAKuo, James论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USASacher, Adrian G.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USABarlesi, Fabrice论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USABesse, Benjamin论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USAKuboki, Yasutoshi论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USADy, Grace K.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USADembla, Vikas论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USAKrauss, John C.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USABurns, Timothy F.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USAKim, June论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USAHenary, Haby论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USANgarmchamnanrith, Gataree论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USALi, Bob T.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
- [6] Efficacy and safety of LY3537982, a potent and highly selective KRAS G12C inhibitor in KRAS G12C-mutant GI cancers: Results from a phase 1 studyJOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (3_SUPPL) : 94 - 94Kuboki, Yasutoshi论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceMurciano-Goroff, Yonina R.论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceYaeger, Rona论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceCassier, Philippe Alexandre论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceHeist, Rebecca Suk论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceFujiwara, Yutaka论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceDeming, Dustin A.论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceAmmakkanavar, Natraj论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FrancePatnaik, Amita论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceShimizu, Toshio论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceCall, Justin论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceHan, Sae-Won论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceFink, Aaron Alan论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceChen, Aaron论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceWillard, Melinda D.论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceBalar, Arjun Vasant论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, FranceKoyama, Takafumi论文数: 0 引用数: 0 h-index: 0机构: Gustave Roussy, Villejuif, France
- [7] Insight towards therapeutic susceptibility of KRAS mutant cancers from MRTX1257, a novel KRAS G12C mutant selective small molecule inhibitorCANCER RESEARCH, 2019, 79 (13)Christensen, James G.论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USAFell, Jay B.论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Mirati Therapeut, San Diego, CA USAMarx, Matthew A.论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USAFischer, John论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Mirati Therapeut, San Diego, CA USAHallin, Jill论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USACalinisan, Andrew论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USABaer, Brian论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Mirati Therapeut, San Diego, CA USABurkhard, Michael论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Mirati Therapeut, San Diego, CA USABlake, James论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Mirati Therapeut, San Diego, CA USAVigers, Guy论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Mirati Therapeut, San Diego, CA USAAranda, Ruth论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USAHargis, Lauren论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USABriere, David论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USAEngstrom, Lars论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USAOlson, Peter论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, San Diego, CA USA Mirati Therapeut, San Diego, CA USA
- [8] Trial in progress: A phase Ib study of AMG 510, a specific and irreversible KRASG12C inhibitor, in combination with other anticancer therapies in patients with advanced solid tumors harboring KRAS p.G12C mutation (CodeBreak 101).JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)Fakih, Marwan论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USADurm, Greg Andrew论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAGovindan, Ramaswamy论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAFalchook, Gerald Steven论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USASoman, Neelesh论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAHenary, Haby Adel论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USAHong, David S.论文数: 0 引用数: 0 h-index: 0机构: City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA
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