Systematic study of high-frequency ultrasonic transducer design for laser-scanning photoacoustic ophthalmoscopy

被引:17
|
作者
Ma, Teng [1 ]
Zhang, Xiangyang [2 ]
Chiu, Chi Tat [1 ]
Chen, Ruimin [1 ]
Shung, K. Kirk [1 ]
Zhou, Qifa [1 ]
Jiao, Shuliang [1 ,2 ]
机构
[1] Univ So Calif, Dept Biomed Engn, Los Angeles, CA 90033 USA
[2] Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USA
基金
美国国家卫生研究院;
关键词
photoacoustics; ultrasonics; microscopy; transducers; ophthalmology; PT SINGLE-CRYSTAL; MICROSCOPY;
D O I
10.1117/1.JBO.19.1.016015
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Photoacoustic ophthalmoscopy (PAOM) is a high-resolution in vivo imaging modality that is capable of providing specific optical absorption information for the retina. A high-frequency ultrasonic transducer is one of the key components in PAOM, which is in contact with the eyelid through coupling gel during imaging. The ultrasonic transducer plays a crucial role in determining the image quality affected by parameters such as spatial resolution, signal-to-noise ratio, and field of view. In this paper, we present the results of a systematic study on a high-frequency ultrasonic transducer design for PAOM. The design includes piezoelectric material selection, frequency selection, and the fabrication process. Transducers of various designs were successfully applied for capturing images of biological samples in vivo. The performances of these designs are compared and evaluated. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
引用
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页数:7
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