Cytochrome P450 2D6

被引：88
|
作者：
Owen, Ryan P. [1 ]
Sangkuhl, Katrin [1 ]
Klein, Teri E. [1 ]
Altman, Russ B. [1 ,2 ]
机构：
[1] Stanford Univ, Med Ctr, Dept Genet, Stanford, CA 94305 USA
[2] Stanford Univ, Med Ctr, Dept Bioengn, Stanford, CA 94305 USA
来源：
PHARMACOGENETICS AND GENOMICS | 2009年 / 19卷 / 07期
关键词：
CYP2D6; pharmacogenetics; pharmacogenomics; PharmGKB; polymorphism; variant; DEBRISOQUINE METABOLISM; CYP2D6; ALLELE; GENE; ASSOCIATION; POPULATION; MUTATIONS; POLYMORPHISMS; SPARTEINE; 2988G-GREATER-THAN-A; IDENTIFICATION;
D O I：
10.1097/FPC.0b013e32832e0e97
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：559 / 562
页数：4
相关论文
共 50 条
  • [21] Treatment of codeine dependence with inhibitors of cytochrome P450 2D6
    Fernandes, LC
    Kilicarslan, T
    Kaplan, HL
    Tyndale, RF
    Sellers, EM
    Romach, MK
    JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2002, 22 (03) : 326 - 329
  • [22] Effect of Desvenlafaxine on the Cytochrome P450 2D6 Enzyme System
    Preskorn, Sheldon H.
    Nichols, Alice I.
    Paul, Jeffrey
    Patroneva, Albena L.
    Helzner, Eileen C.
    Guico-Pabia, Christine J.
    JOURNAL OF PSYCHIATRIC PRACTICE, 2008, 14 (06) : 368 - 378
  • [23] Coumarin substrates for cytochrome P450 2D6 fluorescence assays
    Nakamura, K
    Hanna, IH
    Cai, HL
    Nishimura, Y
    Williams, KM
    Guengerich, FP
    ANALYTICAL BIOCHEMISTRY, 2001, 292 (02) : 280 - 286
  • [24] Inhibitory monoclonal antibodies to human cytochrome P450 2D6
    Krausz, KW
    Yang, TJ
    Gonzalez, FJ
    Shou, MG
    Gelboin, HV
    BIOCHEMICAL PHARMACOLOGY, 1997, 54 (01) : 15 - 17
  • [25] Inhibition of human cytochrome P450 2D6 by schering 66712
    Butler, Brendan Francis
    Palamanda, Jairam
    Nomeir, Amin A.
    Guengerich, F. Peter
    Furge, Laura Lowe
    FASEB JOURNAL, 2007, 21 (05): : A670 - A670
  • [26] Tardive dyskinesia and cytochrome P450 2D6 genotyping in schizophrenia
    Lam, LCW
    Ungvari, GS
    Garcia, M
    Kwong, SL
    Chiu, HFK
    SCHIZOPHRENIA RESEARCH, 2000, 41 (01) : 261 - 261
  • [27] PERSONALIZED PHARMACOTHERAPY IN A PATIENT WITH CYTOCHROME P450 2D6 POLYMORPHISM
    Paul, Sheeba
    Lu, Celia
    Block, Lauren
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2017, 32 : S561 - S562
  • [28] Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4 and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
    Paludetto, Marie-Noeurolle
    Kurkela, Mika
    Kahma, Helina
    Backman, Janne T.
    Niemi, Mikko
    Filppula, Anne M.
    DRUG METABOLISM AND DISPOSITION, 2023, 51 (03) : 293 - 305
  • [29] Human liver cytochrome P450 2D6 genotype, full-length messenger ribonucleic acid, and activity assessed with a novel cytochrome P450 2D6 substrate
    McConnachie, L
    Bodor, M
    Kowdley, K
    Levy, A
    Tung, B
    Thummel, K
    Phillips, B
    Bajpai, M
    Chi, V
    Esmay, JD
    Shen, DA
    Ho, RJY
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 75 (04) : 282 - 297
  • [30] Polymorphisms and phenotypic analysis of cytochrome P450 2D6 in the Tibetan population
    Jin, Tian-Bo
    Ma, Li-Feng
    Zhang, Jia-Yi
    Yuan, Dong-Ya
    Sun, Qiang
    Zong, Ting-Yong
    Geng, Ting-Ting
    Cui, Ya-Li
    Kang, Long-Li
    Chen, Chao
    GENE, 2013, 527 (01) : 360 - 365
12345