Polio Eradication in the World Health Organization African Region, 2008-2012

被引:5
|
作者
Kretsinger, Katrina [1 ]
Gasasira, Alex [2 ]
Poy, Alain [2 ]
Porter, Kimberly A. [1 ]
Everts, Johannes [3 ]
Salla, Mbaye [2 ]
Brown, Kristin H. [1 ]
Wassilak, Steven G. F. [1 ]
Nshimirimana, Deogratias [2 ]
机构
[1] Ctr Dis Control & Prevent, Global Immunizat Div, Atlanta, GA 30333 USA
[2] WHO, Immunizat Vaccines & Emergencies, Reg Off Africa, Brazzaville, Rep Congo
[3] WHO, Strategy Support & Coordinat Unit, Polio Operat & Res, CH-1211 Geneva, Switzerland
来源
关键词
polio eradication; wild poliovirus; WHO Africa Region; Africa; vaccine-derived poliovirus; acute flaccid paralysis; surveillance; WILD POLIOVIRUS; SURVEILLANCE; OUTBREAK; CONGO;
D O I
10.1093/infdis/jiu408
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A renewed commitment at the regional and the global levels led to substantial progress in the fight for polio eradication in the African Region (AFR) of the World Health Organization (WHO) during 2008-2012. In 2008, there were 912 reported cases of wild poliovirus (WPV) infection in 12 countries in the region. This number had been reduced to 128 cases in 3 countries in 2012, of which 122 were in Nigeria, the only remaining country with endemic circulation of WPV in AFR. During 2008-2012, circulation apparently ceased in the 3 AFR countries with reestablished WPV transmission-Angola, the Democratic Republic of the Congo, and Chad. Outbreaks in West Africa continued to occur in 2008-2010 but were more rapidly contained, with fewer cases than during earlier years. This progress has been attributed to better implementation of core strategies, increased accountability, and implementation of innovative approaches. During this period, routine coverage with 3 doses of oral polio vaccine in AFR, as measured by WHO-United Nations Children's Fund estimates, increased slightly, from 72% to 74%. Despite this progress, challenges persist in AFR, and 2013 was marked by new setbacks and importations. High population immunity and strong surveillance are essential to sustain progress and assure that AFR reaches its goal of eradicating WPV.
引用
收藏
页码:S23 / S39
页数:17
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