Cataplexy: An affair of pleasure or an unpleasant affair?

被引：5
|
作者：
Tucci, Valter [1 ,2 ]
Plazzi, Giuseppe [3 ]
机构：
[1] Italian Inst Technol, Dept Neurosci & Brain Technol, I-16163 Genoa, Italy
[2] MRC, Mammalian Genet Unit, Didcot OX11 0RD, Oxon, England
[3] Univ Bologna, Sleep Disorders Ctr, Dept Neurol Sci, Bologna, Italy
来源：
NEUROSCIENCE LETTERS | 2009年 / 450卷 / 02期
关键词：
Narcolepsy; Cataplexy; Emotions; NARCOLEPSY; AMYGDALA; SLEEP; HUMOR;
D O I：
10.1016/j.neulet.2008.11.060
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Narcolepsy, cataplexy and emotions form an intriguing triad that fascinates sleep researchers. A novel aspect of narcoleptic patients' behaviours now appears depending on the emotional valence of the context: how can we explain the fact that narcoleptic patients may experience pleasant-triggered (e.g. laughing) cataplexy as well as unpleasant-related drawback performance (Tucci, V., Stegagno, L, Vandi, S., Ferrillo, F., Palomba, D., Vignatelli, L, Ferini-Strambi, L, Montagna, P., Plazzi, G., Emotional information processing in patients with narcolepsy: a psychophysiologic investigation, Sleep 26 (2003) 558-564; Khatami, R., Birkmann, S., Bassetti, C.L, Amygdala dysfunction in narcolepsycataplexy, J. Sleep Res. 16 (2007) 226-229)? With this in mind we postulate that narcolepsy with cataplexy is a complex sleep disorder that, among others, affects the modulation of emotions at different levels: structural, cellular and molecular. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：90 / 91
页数：2
相关论文
共 50 条
12345