Coordination Complexes of Manganese and Their Biomedical Applications

被引：40
|
作者：
Ali, Basharat [1 ]
Iqbal, Muhammad Adnan [1 ,2 ]
机构：
[1] Univ Agr Faisalabad, Dept Chem, Faisalabad 38040, Punjab, Pakistan
[2] Univ Agr Faisalabad, UAF Community Coll, Faisalabad 38040, Punjab, Pakistan
来源：
CHEMISTRYSELECT | 2017年 / 2卷 / 04期
关键词：
Anticancer; Antimicrobial; Manganese Complexes; Metallodrugs; Mn carboxylates; TRANSITION-METAL-COMPLEXES; SUPEROXIDE-DISMUTASE MIMETICS; IN-VITRO ANTIBACTERIAL; SPECTRAL CHARACTERIZATION; CRYSTAL-STRUCTURES; ANTIMICROBIAL ACTIVITY; BIOLOGICAL-ACTIVITY; SPECTROSCOPIC CHARACTERIZATION; ANTICANCER ACTIVITY; LIGANDS SYNTHESIS;
D O I：
10.1002/slct.201601909
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The clinical success of metallodrugs is rapidly increasing. The historical use of cisplatin and recently a successful marketing of its clinically advanced derivatives (oxaliplatin, carboplatin, nedaplatin, lobaplatin and heptaplatin) for the treatment of various types of cancer has opened new horizons for metal based drugs. Complexes of cobalt, gold, ruthenium, palladium, manganese and even arsenic are either being marketed or close to get success in clinical trials for the treatment of various diseases. Current review compiles the advances on manganese complexes and their biomedical applications. A possible structure activity relationship has been discussed.
引用
收藏
页码：1586 / 1604
页数：19
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