Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa

被引：20
|
作者：
Sugg, R. M. [1 ]
Gonzales, N. R. [1 ]
Matherne, D. E. [1 ]
Ribo, M. [1 ]
Shaltoni, H. M. [1 ]
Baraniuk, S. [1 ]
Noser, E. A. [1 ]
Grotta, J. C. [1 ]
机构：
[1] Univ Texas, Sch Med, Dept Neurol, Houston, TX USA
来源：
NEUROLOGY | 2006年 / 67卷 / 06期
关键词：
D O I：
10.1212/01.wnl.0000239154.51331.c4
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report myocardial injury in 20 recombinant factor VIIa ( rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or received standard medical management. All received EKG and cardiac enzyme testing. Elevated troponin occurred in 20% treated vs 3% nontreated ( p = 0.02). Myocardial infarction occurred in 10% vs 1% ( p = 0.01). We found a significant increase in myocardial injury in rFVIIa treated patients.
引用
收藏
页码：1053 / 1055
页数：3
相关论文
共 50 条
  • [21] Tissue Factor in Brain Is Not Saturated With Factor VIIa Implications for Factor VIIa Dosing in Intracerebral Hemorrhage
    Hoffman, Maureane
    Monroe, Dougald M.
    STROKE, 2009, 40 (08) : 2882 - 2884
  • [22] Hematoma Expansion Shift Analysis: A Novel Approach to Understanding Recombinant Factor VIIa in Intracerebral Hemorrhage
    Parry-Jones, Adrian R.
    STROKE, 2023, 54 (12) : 2999 - 3001
  • [23] Recombinant factor VIIA in traumatic intracerebral hemorrhage: Results of a dose-escalation clinical trial
    Narayan, Raj K.
    Maas, Andrew I. R.
    Marshall, Lawrence F.
    Servadei, Franco
    Skolnick, Brett E.
    Tillinger, Michael N.
    NEUROSURGERY, 2008, 62 (04) : 776 - 786
  • [24] Use of recombinant factor VIIa in massive hemorrhage
    Baranovic, S.
    Rakaric-Poznanovic, M.
    NEUROLOGIA CROATICA, 2004, 53 : 109 - 112
  • [25] Factor VIIa (recombinant) for acute traumatic hemorrhage
    Patanwala, Asad E.
    AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2008, 65 (17) : 1616 - 1623
  • [26] Hemorrhage and Recombinant Factor VIIa A Brief Review
    Scott, Christopher M.
    Trujillo, Tate N.
    ADVANCED EMERGENCY NURSING JOURNAL, 2006, 28 (04) : 284 - 291
  • [27] Recombinant factor VIIa (Novoseven) in hyperacute intracerebral haemorrhage
    Sivakumar, R. M.
    JOURNAL OF NEUROLOGY, 2006, 253 : 139 - 139
  • [28] Recombinant Factor VIIa Treatment for Massive Hemorrhage Patients with Multiple Trauma
    Kim, H.
    Koh, Y.
    Chang, C.
    Lee, E.
    TRANSFUSION, 2011, 51 : 181A - 182A
  • [29] Recombinant factor VIIA in traumatic intracerebral hemorrhage: Results of a dose-escalation clinical trial - Comments
    Marion, Donald W.
    Bullock, Ross M.
    Komotar, Ricardo J.
    Connolly, E. Sander, Jr.
    NEUROSURGERY, 2008, 62 (04) : 786 - 788
  • [30] Rapid warfarin reversal: a 3-factor prothrombin complex concentrate and recombinant factor VIIa cocktail for intracerebral hemorrhage
    Sarode, Ravi
    Matevosyan, Karen
    Bhagat, Ramesh
    Rutherford, Cynthia
    Madden, Christopher
    Beshay, Joseph E.
    JOURNAL OF NEUROSURGERY, 2012, 116 (03) : 491 - 497
12345