Novel Functions of Renin Precursors in Homeostasis and Disease

被引：22
|
作者：
Gomez, R. Ariel [1 ]
Sequeira-Lopez, Maria Luisa S. [1 ]
机构：
[1] Univ Virginia, Sch Med, Child Hlth Res Ctr, Charlottesville, VA 22908 USA
来源：
PHYSIOLOGY | 2016年 / 31卷 / 01期
基金：
美国国家卫生研究院;
关键词：
ANGIOTENSIN-CONVERTING ENZYME; GENE-EXPRESSION; JUXTAGLOMERULAR CELLS; BLOOD-PRESSURE; TUBULAR RENIN; MICE LACKING; MESSENGER-RNA; RAT-KIDNEY; GS-ALPHA; SYSTEM;
D O I：
10.1152/physiol.00039.2015
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.
引用
收藏
页码：25 / 33
页数：9
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