Advanced strategies for combating bacterial biofilms

被引:96
|
作者
Sharahi, Javad Yasbolaghi [1 ]
Azimi, Taher [2 ]
Shariati, Aref [3 ]
Safari, Hossein [4 ]
Tehrani, Melika Khanzadeh [2 ]
Hashemi, Ali [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Med, Dept Microbiol, Tehran, Iran
[2] Univ Tehran Med Sci, Sch Publ Hlth, Dept Pathobiol, Tehran, Iran
[3] Iran Univ Med Sci, Sch Med, Dept Microbiol, Tehran, Iran
[4] Iran Univ Med Sci, Hlth Promot Res Ctr, Tehran, Iran
关键词
antibiofilm molecules; bacterial infection; biofilm; biofilm formation; STREPTOCOCCUS-PYOGENES BIOFILMS; STAPHYLOCOCCUS-AUREUS BIOFILMS; PSEUDOMONAS-AERUGINOSA PAO1; QUORUM SENSING INHIBITORS; CYCLIC DI-GMP; ANTI-BIOFILM; IN-VITRO; LISTERIA-MONOCYTOGENES; ESCHERICHIA-COLI; ANTIBIOFILM EFFICACY;
D O I
10.1002/jcp.28225
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Biofilms are communities of microorganisms that are formed on and attached to living or nonliving surfaces and are surrounded by an extracellular polymeric material. Biofilm formation enjoys several advantages over the pathogens in the colonization process of medical devices and patients' organs. Unlike planktonic cells, biofilms have high intrinsic resistance to antibiotics and sanitizers, and overcoming them is a significant problematic challenge in the medical and food industries. There are no approved treatments to specifically target biofilms. Thus, it is required to study and present innovative and effective methods to combat a bacterial biofilm. In this review, several strategies have been discussed for combating bacterial biofilms to improve healthcare, food safety, and industrial process.
引用
收藏
页码:14689 / 14708
页数:20
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