HEPATOPROTECTIVE EFFECTS OF NGM282 COMPARED TO OBETICHOLIC ACID AND BEZAFIBRATE IN MOUSE MODELS OF CHOLESTASIS

被引:3
|
作者
Luo, J. [1 ]
Ko, B. [1 ]
To, C. [1 ]
Lindhout, D. [1 ]
Ling, L. [1 ]
Chen, J. L. [1 ]
Parsons, T. [1 ]
Rossi, S. [1 ]
DePaoli, A. [1 ]
Tian, H. [1 ]
机构
[1] NGM Biopharmaceut Inc, San Francisco, CA USA
关键词
D O I
10.1016/S0168-8278(14)61475-6
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
P1308
引用
收藏
页码:S531 / S531
页数:1
相关论文
共 50 条
  • [41] Gamma-Aminobutyric Acid in Rice Bran Extract Exerts Antistress Effects in Mouse Models with Depressive-Like Behaviors
    Song, Ji-Hye
    Kim, Hyunhee
    Kong, Min-Jeong
    Hong, Yoon-Taek
    Oh, Su-Jin
    Choi, Kyung-Chul
    JOURNAL OF MEDICINAL FOOD, 2024, 27 (03) : 231 - 241
  • [42] Anti-Diabetic and Anti-Steatotic Effects of a Selective Fatty Acid Synthase Inhibitor Platensimycin in Mouse Models of Diabetes
    Wu, Margaret
    Singh, Shed
    Wang, Jun
    Chung, Christine
    Salituro, Gino
    Karanam, Bindhu
    Lee, Sang Ho
    Powles, Maryann
    Ellsworth, Kenneth
    Lassman, Michael
    Myers, Robert
    Tota, Michael
    Zhang, Bei
    Li, Cai
    DIABETES, 2010, 59 : A202 - A203
  • [43] Oncosis represents the main type of cell death in mouse models of cholestasis:: evidence for a critical role of poly(ADP-ribose) polymerase (PARP) activation in bile acid-induced hepatocytes death
    Fickert, P
    Trauner, M
    Fuchsbichler, A
    Zollner, G
    Wagner, M
    Marschall, HU
    Zartloukal, K
    Denk, H
    Zsengellér, Z
    Szabo, C
    FASEB JOURNAL, 2004, 18 (04): : A558 - A558
  • [44] Co-delivery of evodiamine and rutaecarpine in a microemulsion-based hyaluronic acid hydrogel for enhanced analgesic effects on mouse pain models
    Zhang, Yong-Tai
    Li, Zhe
    Zhang, Kai
    Zhang, Hong-Yu
    He, Ze-Hui
    Xia, Qing
    Zhao, Ji-Hui
    Feng, Nian-Ping
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 528 (1-2) : 100 - 106
  • [45] Anti-tumor and anti-osteolysis effects of the metronomic use of zoledronic acid in primary and metastatic breast cancer mouse models
    Luo, Ke-Wang
    Ko, Chun-Hay
    Yue, Grace G. L.
    Lee, Michelle Y. Y.
    Siu, Wing-Sum
    Lee, Julia K. M.
    Shum, Wai-Ting
    Fung, Kwok-Pui
    Leung, Ping-Chung
    Li, Gang
    Evdokiou, Andreas
    Lau, Clara B. S.
    CANCER LETTERS, 2013, 339 (01) : 42 - 48
  • [46] Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy
    Reschke, Cristina R.
    Silva, Luiz F. Almeida
    Norwood, Braxton A.
    Senthilkumar, Ketharini
    Morris, Gareth
    Sanz-Rodriguez, Amaya
    Conroy, Ronan M.
    Costard, Lara
    Neubert, Valentin
    Bauer, Sebastian
    Farrell, Michael A.
    O'Brien, Donncha F.
    Delanty, Norman
    Schorge, Stephanie
    Pasterkamp, R. Jeroen
    Rosenow, Felix
    Henshall, David C.
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2017, 6 : 45 - 56
  • [47] Omega-3-Acid Ethyl Esters Block the Protumorigenic Effects of Obesity in Mouse Models of Postmenopausal Basal-like and Claudin-Low Breast Cancer
    Ford, Nikki A.
    Rossi, Emily L.
    Barnett, Kelsey
    Yang, Peiying
    Bowers, Laura W.
    Hidaka, Brandon H.
    Kimler, Bruce F.
    Carlson, Susan E.
    Shureiqi, Imad
    deGraffenried, Linda A.
    Fabian, Carol J.
    Hursting, Stephen D.
    CANCER PREVENTION RESEARCH, 2015, 8 (09) : 796 - 806
  • [48] Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight (vol 33, 831.e21, 2012)
    Amtul, Zareen
    Uhrig, Markus
    Wang, Lin
    Rozmahel, Richard F.
    Beyreuther, Konrad
    NEUROBIOLOGY OF AGING, 2018, 62 : 247 - 247
  • [49] Regulation of Hepatocellular Fatty Acid Uptake in Mouse Models of Fatty Liver Disease with and without Functional Leptin Signaling: Roles of NfKB and SREBP-1C and the Effects of Spexin
    Ge, Jasmine F.
    Walewski, J. L.
    Anglade, D.
    Berk, P. D.
    SEMINARS IN LIVER DISEASE, 2016, 36 (04) : 360 - 372
  • [50] Hypoxia inducible factor (HIF) inhibitor 64B has superior anti-tumor effects compared to two different tyrosine kinase inhibitors when tested in mouse models of uveal melanoma
    Yang, Hua
    Grossniklaus, Hans E.
    Van Meir, Erwin G.
    Offermann, Margaret K.
    CANCER RESEARCH, 2023, 83 (07)