Cost-effectiveness analysis of gestational diabetes mellitus screening in France

Objective: To compare three strategies for gestational diabetes screening (i) screening of high-risk pregnant women with the 50g oral glucose tolerance test (OGTT): (ii) screening of all pregnant women with the 50 OGTT (iii) screening of all pregnant women according to the 75 g OGTT. Study design: Cost-effectiveness analysis. The outcome measures, i.e. macrosonita, prematurity, perinatal mortality, hypertensive disorders rates were estimated from published studies and the costs from a prospective study inolving 120 pregnant women. Results: Compared to the first strategy, the cost to obtain one unit of additional effectiveness with the second screening strategy. was up to I times more expensive. and with the third strategy was up to 3.7 times more expensive. Conclusion: The cost,, per case prevented reflect a favourable cost-effectiveness ratio (CER) for screening of high-risk pregnant women by 50 oral glucose test. (C) 2002 ELsevier Science Ireland Ltd. All rights reserved.