House dust mite sublingual immunotherapy in allergic rhinitis

被引:7
|
作者
Cho, Sung-Woo [1 ]
Han, Doo Hee [2 ]
Kim, Jeong-Whun [1 ]
Kim, Dong-Young [2 ]
Rhee, Chae-Seo [1 ,3 ,4 ]
机构
[1] Seoul Natl Univ, Coll Med, Bundang Hosp, Dept Otorhinolaryngol Head & Neck Surg, 82 Gumi Ro 173beon Gil, Seongnam 13620, South Korea
[2] Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Otorhinolaryngol Head & Neck Surg, Seoul 03080, South Korea
[3] Seoul Natl Univ, Med Res Ctr, Res Ctr Sensory Organs, Seoul 03080, South Korea
[4] Seoul Natl Univ, Inst Allergy Clin Immunol, Med Res Ctr, Seoul 03080, South Korea
关键词
allergic rhinitis; house dust mite; sublingual immunotherapy; DOUBLE-BLIND; ASTHMATIC-CHILDREN; CLINICAL-EFFICACY; SUBCUTANEOUS IMMUNOTHERAPY; IMMUNOLOGICAL MECHANISMS; TABLET; ADULTS; RHINOCONJUNCTIVITIS; SENSITIZATION; SAFETY;
D O I
10.2217/imt-2018-0013
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Allergen immunotherapy has been shown to be effective in treatment of allergic rhinitis (AR). Sublingual immunotherapy (SLIT) is generally recommended for treating seasonal AR in adults and children; however, questions remain in regard to AR treatment in relation to house dust mite (HDM). Due to heterogeneous formulations, different outcome reporting systems, and the lack of a standardized dose, HDM SLITs have not been standardized in published studies. Nevertheless, studies continuously report positive effects of HDM SLIT in AR, and HDM SLIT remains a treatment option for patients with HDM-induced allergic asthma that frequently co-exists with AR. Therefore, it is likely that HDM SLIT usage will increase. This review will focus on HDM SLIT in AR exclusively.
引用
收藏
页码:567 / 578
页数:12
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