LONG-TERM PRECLINICAL SAFETY EVALUATION OF CLINICAL-GRADE HUMAN NEURAL STEM CELLS IN RODENT MODEL OF TRAUMATIC BRAIN INJURY

被引：0
|
作者：
Gajavelli, Shyam [1 ]
Spurlock, Markus S. [1 ]
Hu, Zhen [1 ]
Sirsy, Angie [1 ]
Mahavadi, Anil [1 ]
Gultekin, Sakir H. [1 ]
Shear, Deborah A. [2 ]
Bullock, Ross M. [1 ]
Lujan, Maria M. [1 ]
机构：
[1] Univ Miami, Miami Project Cure Paralysis, Miami, FL USA
[2] Walter Reed Army Inst Res, Brain Trauma Neuroprotect, Silver Spring, MD USA
来源：
JOURNAL OF NEUROTRAUMA | 2019年 / 36卷 / 13期
关键词：
human neural stem cells; tumorigenicity; TBI; Penetrating; Neuroprotection;
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A16-04
引用
收藏
页码：A77 / A78
页数：2
相关论文
共 50 条
  • [21] The Effect of Oral Mucosal Mesenchymal Stem Cells on Pathological and Long-Term Outcomes in Experimental Traumatic Brain Injury
    Dehghanian, Fatemeh
    Soltani, Zahra
    Farsinejad, Alireza
    Khaksari, Mohammad
    Jafari, Elham
    Darakhshani, Ali
    Sabet, Nazanin
    Bashiri, Hamideh
    BIOMED RESEARCH INTERNATIONAL, 2022, 2022
  • [22] Long term survival and functional efficacy of transplanted neural stem cells in a mouse model of traumatic brain surgery
    Shear, DA
    Tate, MC
    Archer, DR
    Hoffman, SW
    Haik, KL
    Hulce, VD
    LaPlaca, MC
    Stein, DG
    EXPERIMENTAL NEUROLOGY, 2002, 175 (02) : 421 - 421
  • [23] Therapeutic evaluation of mesenchymal stem cells and their secretome in a model of traumatic brain injury
    Lin, Mao-Tsun
    Chio, Chung-Ching
    Chang, Ching-Ping
    BRAIN INJURY, 2016, 30 (5-6) : 643 - 643
  • [24] FDA-APPROVED HUMAN FETAL-DERIVED NEURAL STEM CELLS FAIL TO IMPROVE COGNITIVE OR MOTOR OUTCOME IN A RODENT MODEL OF TRAUMATIC BRAIN INJURY
    Okada-Rising, Starlyn
    Pedersen, Rebecca
    Figiel, Caitlin
    Huynh, Linda
    Cao, Ying
    Gilsdorf, Janice
    Shear, Deborah
    JOURNAL OF NEUROTRAUMA, 2022, 39 (11-12) : A57 - A57
  • [25] Short term and long term behavioural and pathological changes in a novel rodent model of repetitive mild traumatic brain injury
    McAteer, K.
    Corrigan, F.
    Thornton, E.
    Heuvel, C. V. D.
    Turner, R.
    Vink, R.
    JOURNAL OF NEUROCHEMISTRY, 2015, 134 : 340 - 341
  • [26] Long-Term Survival of Human Neural Stem Cells in the Ischemic Rat Brain upon Transient Immunosuppression
    Nodari, Laura Rota
    Ferrari, Daniela
    Giani, Fabrizio
    Bossi, Mario
    Rodriguez-Menendez, Virginia
    Tredici, Giovanni
    Delia, Domenico
    Vescovi, Angelo Luigi
    De Filippis, Lidia
    PLOS ONE, 2010, 5 (11):
  • [27] The accuracy of artificial neural networks in predicting long-term outcome after traumatic brain injury
    Segal, Mary E.
    Goodman, Philip H.
    Goldstein, Richard
    Hauck, Walter
    Whyte, John
    Graham, John W.
    Polansky, Marcia
    Hammond, Flora M.
    JOURNAL OF HEAD TRAUMA REHABILITATION, 2006, 21 (04) : 298 - 314
  • [28] Long-Term Effects of Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease
    Zysk, Marlena
    Clausen, Fredrik
    Aguilar, Ximena
    Sehlin, Dag
    Syvanen, Stina
    Erlandsson, Anna
    JOURNAL OF ALZHEIMERS DISEASE, 2019, 72 (01) : 161 - 180
  • [29] Short and Long Term Behavioral and Pathological Changes in a Novel Rodent Model of Repetitive Mild Traumatic Brain Injury
    McAteer, Kelly M.
    Corrigan, Frances
    Thornton, Emma
    Turner, Renee Jade
    Vink, Robert
    PLOS ONE, 2016, 11 (08):
  • [30] Exosome Derived from Human Neural Stem Cells Improves Motor Activity and Neurogenesis in a Traumatic Brain Injury Model
    Abedi, Mahsa
    Hajinejad, Mehrdad
    Atabi, Fereshteh
    Sahab-Negah, Sajad
    BIOMED RESEARCH INTERNATIONAL, 2022, 2022
12345