Reference regions of two or more dimensions

被引:18
|
作者
Boyd, JC [1 ]
机构
[1] Univ Virginia Hlth Syst, Dept Pathol, Charlottesville, VA 22901 USA
关键词
Mahalonobis distance; multivariate Normal distribution; multivariate reference region; Normalizing transformation; univariate reference interval;
D O I
10.1515/CCLM.2004.125
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Despite being proposed over 30 years ago, the multivariate reference region (MRR) remains an interpretive tool with uncertain value in clinical practice. This paper reviews the mathematical theory of the MRR, presents topics in the clinical application of MRRs, and examines the advantages and disadvantages of MRRs. Finally, some thoughts are offered regarding future directions for work in this field.
引用
收藏
页码:739 / 746
页数:8
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