Structure-based design of small-molecular inhibitors targeting the Menin-MLL protein-protein interaction

被引：0

作者：

Xu, Shilin ^{[1
]}

Xu, Tianfeng ^{[1
]}

Zheng, Ke ^{[1
]}

Aguilar, Angelo ^{[1
]}

Huang, Liyue ^{[1
]}

Bernard, Denzil ^{[1
]}

McEachern, Donna ^{[1
]}

Przybranowski, Sally ^{[1
]}

Stuckey, Jeanne ^{[1
]}

Wang, Shaomeng ^{[1
]}

机构：

[1] Univ Michigan, Ann Arbor, MI 48109 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 253卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

236

引用

页数：1

共 50 条

[1] Development of small molecule inhibitors of the menin-MLL protein-protein interaction for cancer therapy"
Grembecka, Jolanta
Borkin, Dmitry
Miao, Hongzhi
Kempinska, Katarzyna
Pollock, Jonathan
Purohit, Trupta
Klossowski, Szymon
Sun, Duxin
Cierpicki, Tomasz
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
[2] Menin-MLL protein-protein interaction inhibitors: a patent review (2021-present)
Wang, Fang
Yang, Zhe
Wu, Yujie
Bai, Huanrong
Xin, Minhang
EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 35 (01) : 65 - 78
[3] Menin-MLL protein-protein interaction inhibitors: a patent review (2014-2021)
Bai, Huanrong
Zhang, San-Qi
Lei, Hao
Wang, Fang
Ma, Mengyan
Xin, Minhang
EXPERT OPINION ON THERAPEUTIC PATENTS, 2022, 32 (05) : 507 - 522
[4] Structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and mixed lineage leukemia (MLL)
Pollock, Jonathan
Borkin, Dmitry
Kempinska, Katarzyna
Purohit, Trupta
Li, Xiaoqin
Wen, Bo
Zhao, Ting
Miao, Hongzhi
Shukla, Shirish
He, Miao
Sun, Duxin
Cierpicki, Tomasz
Grembecka, Jolanta
CANCER RESEARCH, 2016, 76
[5] Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction
Xu, Shilin
Aguilar, Angelo
Xu, Tianfeng
Zheng, Ke
Huang, Liyue
Stuckey, Jeanne
Chinnaswamy, Krishnapriya
Bernard, Denzil
Fernandez-Salas, Ester
Liu, Liu
Wang, Mi
McEachern, Donna
Przybranowski, Sally
Foster, Caroline
Wang, Shaomeng
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (06) : 1601 - 1605
[6] Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction
Aguilar, Angelo
Zheng, Ke
Xu, Tianfeng
Xu, Shilin
Huang, Liyue
Fernandez-Salas, Ester
Liu, Liu
Bernard, Denzil
Harvey, Kaitlin P.
Foster, Caroline
McEachern, Donna
Stuckey, Jeanne
Chinnaswamy, Krishnapriya
Delproposto, James
Kampf, Jeff W.
Wang, Shaomeng
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (13) : 6015 - 6034
[7] Structure-based screening and optimization of cytisine derivatives as inhibitors of the menin-MLL interaction
Zhong, Hai-Jing
Lee, Bo Ra
Boyle, Joshua William
Wang, Wanhe
Ma, Dik-Lung
Chan, Philip Wai Hong
Leung, Chung-Hang
CHEMICAL COMMUNICATIONS, 2016, 52 (34) : 5788 - 5791
[8] Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)
Borkin, Dmitry
Pollock, Jonathan
Kempinska, Katarzyna
Purohit, Trupta
Li, Xiaoqin
Wen, Bo
Zhao, Ting
Miao, Hongzhi
Shukla, Shirish
He, Miao
Sun, Duxin
Cierpicki, Tomasz
Grembecka, Jolanta
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (03) : 892 - 913
[9] Design and optimization of small molecule inhibitors blocking the menin-MLL interaction
Xu, Tianfeng
Xu, Shilin
Zheng, Ke
Aguilar, Angelo
Huang, Liyue
Chinnaswamy, Krishnapriya
Bernard, Denzil
McEachern, Donna
Przybranowski, Sally
Stuckey, Jeanne
Wang, Shaomeng
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
[10] Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide
Yue, Liyan
Du, Juanjuan
Ye, Fei
Chen, Zhifeng
Li, Lianchun
Lian, Fulin
Zhang, Bidong
Zhang, Yuanyuan
Jiang, Hualiang
Chen, Kaixian
Li, Yuanchao
Zhou, Bing
Zhang, Naixia
Yang, Yaxi
Luo, Cheng
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 14 (36) : 8503 - 8519

← 1 2 3 4 5 →