Validation of the Korean Stroop Test in Diagnosis of Minimal Hepatic Encephalopathy

被引：10

作者：

Yoon, Eileen L. ^{[1
]}

Jun, Dae Won ^{[2
]}

Jeong, Jae Yoon ^{[3
]}

Kim, Tae Yeob ^{[4
]}

Song, Do Seon ^{[5
]}

Ahn, Sang Bong ^{[6
]}

Kim, Hee Yeon ^{[7
]}

Jung, Young Kul ^{[8
]}

Song, Myeong Jun ^{[9
]}

Kim, Sung Eun ^{[10
]}

Kim, Hyoung Su ^{[11
]}

Jeong, Soung Won ^{[12
]}

Kim, Sang Gyune ^{[13
]}

Lee, Tae Hee ^{[14
]}

Cho, Yong Kyun ^{[15
]}

Kim, Jae-Kwan ^{[16
]}

Ryu, Hokyoung ^{[16
]}

机构：

[1] Inje Univ, Sanggye Paik Hosp, Dept Internal Med, Coll Med, Seoul 01757, South Korea

[2] Hanyang Univ, Hanyang Univ Hosp, Dept Internal Med, Coll Med, Seoul 04763, South Korea

[3] Hanyang Univ, Guri Hosp, Dept Internal Med, Coll Med, Guri Si 11923, South Korea

[4] New Hope Internal Med Clin, Dept Internal Med, Seoul 03113, South Korea

[5] Catholic Univ Korea, Coll Med, Dept Internal Med, St Vincents Hosp, Suwon 16247, South Korea

[6] Eulji Univ, Coll Med, Dept Internal Med, Nowon Eulji Med Ctr, Seoul 01830, South Korea

[7] Catholic Univ Korea, Coll Med, Dept Internal Med, Uijeongbu St Marys Hosp, Uijeongbu Si 11765, South Korea

[8] Korea Univ, Med Ctr, Dept Internal Med, Ansan 02841, South Korea

[9] Catholic Univ Korea, Coll Med, Dept Internal Med, Daejeon St Marys Hosp, Daejeon 34943, South Korea

[10] Hallym Univ, Coll Med, Dept Internal Med, Sacred Heart Hosp, Anyang Si 14068, South Korea

[11] Hallym Univ, Coll Med, Dept Internal Med, Kangdong Sacred Heart Hosp, Seoul 05355, South Korea

[12] Soonchunhyang Univ, Coll Med, Dept Internal Med, Seoul Hosp, Seoul 04401, South Korea

[13] Soonchunhyang Univ, Coll Med, Dept Internal Med, Bucheon Hosp, Bucheon Si 14584, South Korea

[14] Konyang Univ, Coll Med, Dept Internal Med, Daejeon 35365, South Korea

[15] Sungkyunkwan Univ, Sch Med, Dept Internal Med, Kangbuk Samsung Hosp, Seoul 03181, South Korea

[16] Hanyang Univ, Dept Arts & Technol, Seoul 04763, South Korea

来源：

SCIENTIFIC REPORTS | 2019年 / 9卷 / 1期

关键词：

ENCEPHALAPP; CIRRHOSIS; COVERT; SCORE;

D O I：

10.1038/s41598-019-44503-w

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The burden of minimal hepatic encephalopathy (MHE) is significant, but no universal criteria for diagnosis have been established. We aimed to validate the Korean Stroop Test for MHE screening. Chronic hepatitis B-related liver cirrhosis patients were recruited prospectively from 13 centers. The Korean Stroop Test consisted of two Stroop-off states (color and word) and two Stroop-on states (inhibition and switching). Accuracy adjusted psychomotor speed (rate correct score) of these tests were analyzed. Sex- and age- adjusted rate correct scores of these tests were rated as the Korean Stroop Score (K-Stroop score). MHE was diagnosed when Portosystemic Encephalopathy Syndrome Test (PHES) scores were below -4. A total of 220 liver cirrhosis patients and 376 healthy controls were enrolled. Prevalence of MHE was 20.6% in cirrhosis patients. Rate correct scores and the K-Stroop score showed significant differences between healthy controls, cirrhosis patients without MHE, and cirrhosis patients with MHE. The rate correct score of the K-Stroop score was 0.74 (95% Confidence Interval: 0.66-0.83, P < 0.001). Female gender and the K-Stroop score were significant for MHE diagnosis. The Korean Stroop Test is simple and valid for screening of MHE.

引用

页数：8

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