1,25(OH)2D AND IL-6 BLOCKADE SYNERGISTICALLY REGULATES RHEUMATOID ARTHRITIS VIA SUPPRESSION OF TH17 AND OSTEOCLASTOGENESIS

被引：0
|
作者：
Kim, Moon Young [1 ]
Lee, Jennifer [1 ]
Park, Sung-Hwan [1 ]
机构：
[1] Catholic Univ Korea, Div Rheumatol, Dept Internal Med, Seoul St Marys Hosp,Coll Med, Seoul, South Korea
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2019年 / 78卷
关键词：
D O I：
10.1136/annrheumdis-2019-eular.3857
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
SAT0153
引用
收藏
页码：1148 / 1149
页数：2
相关论文
共 50 条
  • [21] 1,25(OH) 2D3 MODULATES GENE EXPRESSION INVOLVED IN CYTOKINE PRODUCTION, PROLIFERATION, SURVIVAL AND MIGRATION OF TH17 CELLS FROM PATIENTS WITH RHEUMATOID ARTHRITIS
    Dankers, W.
    van Hamburg, J. P.
    Asmawidjaja, P. S.
    Davelaar, N.
    Wen, K.
    Mus, A. M. C.
    Colin, E. M.
    van Leeuwen, J. P. T. M.
    Hazes, J. M. W.
    Lubberts, E.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 71 : 101 - 101
  • [22] 1,25(OH)2D3 MODULATES GENE EXPRESSION INVOLVED IN CYTOKINE PRODUCTION, PROLIFERATION, SURVIVAL AND MIGRATION OF TH17 CELLS FROM PATIENTS WITH RHEUMATOID ARTHRITIS
    Dankers, Wendy
    van Hamburg, Jan Piet
    Asmawidjaja, Patrick S.
    Davelaar, Nadine
    Wen, K.
    Mus, Adriana M. C.
    Colin, Edgar M.
    van Leeuwen, Johannes P. T. M.
    Hazes, Johanna M. W.
    Lubberts, Erik
    ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 : A17 - A17
  • [23] CORRELATION BETWEEN 1,25(OH)2D LEVELS AND IL-1 OR IL-2 LEVELS IN RHEUMATOID SYNOVIAL-FLUID
    INABA, M
    GOTO, H
    YUKIOKA, K
    FURUMITSU, Y
    YUTANI, Y
    ARTHRITIS AND RHEUMATISM, 1995, 38 (09): : 78 - 78
  • [24] 1,25(OH)2D3 SUPPRESSES THE PRO-INFLAMMATORY TH17 RASF FEEDBACK LOOP VIA IL-4-DEPENDENT AND -INDEPENDENT MECHANISMS
    Dankers, W.
    van Hamburg, J. P.
    Razawy, W.
    Davelaar, N.
    Mus, A. M. C.
    Asmawidjaja, P. S.
    van Leeuwen, J. P. T. M.
    Colin, E. M.
    Lubberts, E.
    ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : A69 - A69
  • [25] 1,25（OH）D体外抑制小鼠Th17细胞分化的作用研究
    顾磊
    蒋春晖
    孙隆慈
    刘晔
    周鸿
    许春杰
    徐庆
    肝胆胰外科杂志, 2016, (03) : 213 - 216
  • [26] Increased IL-6 expression on THP-1 by IL-34 stimulation up-regulated rheumatoid arthritis Th17 cells
    Bing Wang
    Yawei Tang
    Xiaotong Sun
    Xunli Ouyang
    Han Li
    Jing Wei
    Yan Zhang
    Xia Li
    Clinical Rheumatology, 2018, 37 : 127 - 137
  • [27] Increased IL-6 expression on THP-1 by IL-34 stimulation up-regulated rheumatoid arthritis Th17 cells
    Wang, Bing
    Tang, Yawei
    Sun, Xiaotong
    Ouyang, Xunli
    Li, Han
    Wei, Jing
    Zhang, Yan
    Li, Xia
    CLINICAL RHEUMATOLOGY, 2018, 37 (01) : 127 - 137
  • [28] MRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis
    Dong-Gun Lee
    Jung-Won Woo
    Seung-Ki Kwok
    Mi-La Cho
    Sung-Hwan Park
    Experimental & Molecular Medicine, 2013, 45 : e20 - e20
  • [29] 1,25(OH)2D3 Protects Liver Fibrosis Through Decreasing the Generation of TH17 Cells
    Gu, Lei
    Xu, Qing
    Cao, Hui
    MEDICAL SCIENCE MONITOR, 2017, 23 : 2049 - 2058
  • [30] POSITIVE CORRELATION BETWEEN 1,25(OH)2D LEVELS AND IL-1 OR IL-2 LEVELS IN RHEUMATOID SYNOVIAL-FLUID
    MURANO, M
    INABA, M
    YUKIOKA, K
    GOTO, H
    FURUMITSU, Y
    YUTANI, Y
    NISHIZAWA, Y
    MORII, H
    JOURNAL OF BONE AND MINERAL RESEARCH, 1995, 10 : S390 - S390
12345