DEVELOPMENT OF A RELAY ASSAY WITH PLATED HUMAN HEPATOCYTES FOR THE EVALUATION OF SLOWLY METABOLIZED COMPOUNDS

被引:0
|
作者
Doshi, Utkarsh [1 ]
Li, Albert P. [1 ]
机构
[1] In Vitro ADMET Labs LLC, Columbia, MD USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P29
引用
收藏
页码:54 / 54
页数:1
相关论文
共 50 条
  • [41] Assessment of Illumina® Human mtDNA Genome assay: workflow evaluation with development of analysis and interpretation guidelines
    Sukser, Viktorija
    Rokic, Filip
    Barbaric, Lucija
    Korolija, Marina
    INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2021, 135 (04) : 1161 - 1178
  • [42] Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression
    Chakrapani, Baby P. S.
    Kumar, Sandeep
    Subramaniam, Jamuna R.
    JOURNAL OF BIOSCIENCES, 2008, 33 (02) : 269 - 277
  • [43] Development and evaluation of a new rapid assay for the detection of total IgE in human serum and capillary blood
    Lucassen, R.
    Mahler, M.
    Fooke, M.
    ALLERGY, 2008, 63 : 531 - 532
  • [44] Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression
    Baby P. S. Chakrapani
    Sandeep Kumar
    Jamuna R. Subramaniam
    Journal of Biosciences, 2008, 33 : 269 - 277
  • [45] Assessment of Illumina® Human mtDNA Genome assay: workflow evaluation with development of analysis and interpretation guidelines
    Viktorija Sukser
    Filip Rokić
    Lucija Barbarić
    Marina Korolija
    International Journal of Legal Medicine, 2021, 135 : 1161 - 1178
  • [46] Evaluation of the effects produced by volatile organic compounds (VOCs) over human embryo development
    Vasquez, V.
    Beltran, D.
    Remohi, J.
    Santos, J. M. De Los
    Galan, A.
    Perez, S.
    Mercader, A.
    De Los Santos, M. J.
    HUMAN REPRODUCTION, 2016, 31 : 45 - 46
  • [47] Use of a human microsomal library for metabolite elucidation, assay development and biological monitoring of occupationally relevant compounds.
    Striley, CAF
    Snawder, JE
    Biagini, RE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U59 - U59
  • [48] Development of a high-throughput human rhinovirus infectivity cell-based assay for identifying antiviral compounds
    Phillips, Tim
    Jenkinson, Lesley
    McCrae, Christopher
    Thong, Bob
    Unitt, John
    JOURNAL OF VIROLOGICAL METHODS, 2011, 173 (02) : 182 - 188
  • [49] Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
    Digles, Daniela
    Ingles-Prieto, Alvaro
    Dvorak, Vojtech
    Mocking, Tamara A. M.
    Goldmann, Ulrich
    Garofoli, Andrea
    Homan, Evert J.
    Di Silvio, Alberto
    Azzollini, Lucia
    Sassone, Francesca
    Fogazza, Mario
    Baerenz, Felix
    Pommereau, Antje
    Zuschlag, Yasmin
    Ooms, Jasper F.
    Tranberg-Jensen, Jeppe
    Hansen, Jesper S.
    Stanka, Josefina
    Sijben, Hubert J.
    Batoulis, Helena
    Bender, Eckhard
    Martini, Riccardo
    Ijzerman, Adriaan P.
    Sauer, David B.
    Heitman, Laura H.
    Manolova, Vania
    Reinhardt, Juergen
    Ehrmann, Alexander
    Leippe, Philipp
    Ecker, Gerhard F.
    Huber, Kilian V. M.
    Licher, Thomas
    Scarabottolo, Lia
    Wiedmer, Tabea
    Superti-Furga, Giulio
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [50] A 384-well plate high throughput assay for the evaluation of time-dependent inhibition of CYP3A4 in human hepatocytes
    Doshi, Utkarsh
    Li, Albert P.
    DRUG METABOLISM REVIEWS, 2016, 48 : 86 - 87