Prognosis and Disclosure of Functional Modules from Protein-Protein Interaction Network

被引:0
|
作者
Modi, Manali R. [1 ]
Merry, K. P. [2 ]
机构
[1] Marwadi Educ Fdn Grp Inst, Dept Comp Engn, Rajkot, Gujarat, India
[2] Marwadi Educ Fdn Grp Inst, Dept Informat Technol, Rajkot, Gujarat, India
关键词
Prognosis; disclosure; PPI network; functional modules; protein; detection methods; inferring PPI network;
D O I
10.1145/2791405.2791442
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Bioinformatics is an integrated area of data mining, statistics and computational biology. Proteins are the building bit of the living creatures and it assumes transcendent part to fulfill natural procedures of the life forms. Protein-Protein Interaction (PPI) network is a sort of system that delineates the fundamental part in organic exercises. PM is the corner stone of all the biological processes occurring in the organisms. In PPI network, protein interacts with one another to incorporate large molecules. Functional module detection refers to the set of proteins which partake in the same organic courses of biological action. There are number of approaches which are used as a part of recognizing useful modules from the PPI system. Clustering in the PPI system setting assembles proteins which impart a bigger number of communications. The consequences of clustering can clarify the construction of the PPI arrangement and prescribe possible limits for detecting modules which were at one time uncharacterized. The functional module prognosis and disclosure using clustering methods helps in better understanding of the biological mechanism of an organism which in turn contributes towards the remedies of various diseases.
引用
收藏
页码:25 / 30
页数:6
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