Linkage analysis between schizophrenia and the Darier's disease region on 12q

被引:6
|
作者
OMalley, MP
Bassett, AS
Honer, WG
Kennedy, JL
King, N
Berg, D
机构
[1] UNIV TORONTO,DIV DERMATOL,TORONTO,ON M5S 1B2,CANADA
[2] WOMENS COLL HOSP,TORONTO,ON M5S 1B2,CANADA
[3] UNIV TORONTO,DEPT PSYCHIAT,TORONTO,ON,CANADA
[4] QUEEN ST MENTAL HLTH CTR,TORONTO,ON,CANADA
[5] UNIV BRITISH COLUMBIA,DEPT PSYCHIAT,VANCOUVER,BC V5Z 1M9,CANADA
[6] CLARKE INST PSYCHIAT,TORONTO,ON M5T 1R8,CANADA
基金
加拿大健康研究院;
关键词
chromosome; 12; Darier's disease; linkage; schizophrenia;
D O I
10.1097/00041444-199624000-00003
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
There have been reports of an association between Darier's disease, an autosomal dominant genodermatosis, and psychiatric illness. Recently the gene causing Darier's disease has been mapped to an area an 12q, between D12S58 and D12S84. The findings of linkage analysis of 4 markers in the Darier's disease region on 12q in five families segregating schizophrenia are presented. They fail to support close linkage between schizophrenia and the Darier's disease region on 12q.
引用
收藏
页码:187 / 190
页数:4
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