Evolving health care through personal genomics

被引：75
|
作者：
Rehm, Heidi L. [1 ,2 ,3 ,4 ]
机构：
[1] Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
[3] Partners Healthcare Personalized Med, Mol Med Lab, Cambridge, MA 02139 USA
[4] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
来源：
NATURE REVIEWS GENETICS | 2017年 / 18卷 / 04期
基金：
美国国家卫生研究院;
关键词：
LUNG-CANCER; ADJUVANT CHEMOTHERAPY; DIAGNOSTIC ODYSSEY; GENETIC-VARIATION; MUTATIONS; SEQUENCE; CARDIOMYOPATHY; LABORATORIES; TRASTUZUMAB; ASSOCIATION;
D O I：
10.1038/nrg.2016.162
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
With the rapid evolution of next-generation DNA sequencing technologies, the cost of sequencing a human genome has plummeted, and genomics has started to pervade health care across all stages of life-from preconception to adult medicine. Challenges to fully embracing genomics in a clinical setting remain, but some approaches are starting to overcome these barriers, such as community-driven data sharing to improve the accuracy and efficiency of applying genomics to patient care. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
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页码：259 / 267
页数：9
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