ANTI-TUBERCULOSIS DRUG RESISTANCE AND HIV CO-INFECTION IN PHNOM PENH, CAMBODIA

被引：0
|
作者：
Sar, Borann [1 ]
Keo, Chantary [1 ]
Leng, Chanthy [2 ]
Saman, Manil [2 ]
Min, Doung Chan [2 ]
Chan, Sarin [2 ]
Monchy, Didier [1 ]
Sarthou, Jean-Louis [1 ,2 ]
机构：
[1] Inst Pasteur Cambodge, Lab Mycobacteriol, Unit Clin Testing, Phnom Penh, Cambodia
[2] Inst Pasteur Cambodge, Dept Epidemiol, Phnom Penh, Cambodia
来源：
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH | 2009年 / 40卷 / 01期
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D O I：
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中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The objective of this study was to observe the prevalence of drug resistance in Mycobacterium tuberculosis isolates in HIV associated tuberculosis co-infected patients in Phnom Penh City. The isolates of M. tuberculosis were collected during active laboratory-based surveillance. Of the 98 isolates studied, M. tuberculosis resistance to isoniazid was seen in 23.5%, resistance to rifampicin was seen in 16.3% and multidrug-resistance (MDR-TB) was seen in 5.1%. Our findings reveal an alarmingly high level of resistance to isoniazid and rifampicin, and confirms the need for drug susceptibility testing to guide treatment in patients with culture positive tuberculosis.
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页码：104 / 107
页数：4
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