ANTI-TUBERCULOSIS DRUG RESISTANCE AND HIV CO-INFECTION IN PHNOM PENH, CAMBODIA

被引：0

作者：

Sar, Borann ^{[1
]}

Keo, Chantary ^{[1
]}

Leng, Chanthy ^{[2
]}

Saman, Manil ^{[2
]}

Min, Doung Chan ^{[2
]}

Chan, Sarin ^{[2
]}

Monchy, Didier ^{[1
]}

Sarthou, Jean-Louis ^{[1
,2
]}

机构：

[1] Inst Pasteur Cambodge, Lab Mycobacteriol, Unit Clin Testing, Phnom Penh, Cambodia

[2] Inst Pasteur Cambodge, Dept Epidemiol, Phnom Penh, Cambodia

来源：

SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH | 2009年 / 40卷 / 01期

关键词：

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The objective of this study was to observe the prevalence of drug resistance in Mycobacterium tuberculosis isolates in HIV associated tuberculosis co-infected patients in Phnom Penh City. The isolates of M. tuberculosis were collected during active laboratory-based surveillance. Of the 98 isolates studied, M. tuberculosis resistance to isoniazid was seen in 23.5%, resistance to rifampicin was seen in 16.3% and multidrug-resistance (MDR-TB) was seen in 5.1%. Our findings reveal an alarmingly high level of resistance to isoniazid and rifampicin, and confirms the need for drug susceptibility testing to guide treatment in patients with culture positive tuberculosis.

引用

页码：104 / 107

页数：4

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