KIDNEY CANCER Progress and controversies in neoadjuvant therapy

被引：13

作者：

Posadas, Edwin M. ^{[1
]}

Figlin, Robert A. ^{[1
]}

机构：

[1] Cedars Sinai Med Ctr, Urol Oncol Program, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA

来源：

NATURE REVIEWS UROLOGY | 2014年 / 11卷 / 05期

关键词：

PATHOLOGICAL COMPLETE RESPONSE; RENAL-CELL CARCINOMA; RADICAL PROSTATECTOMY; BLADDER-CANCER; SURVIVAL; TRIAL; CHEMOTHERAPY; CYSTECTOMY;

D O I：

10.1038/nrurol.2014.89

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Use of clinically active agents, such as kinase inhibitors, before nephrectomy is safe and feasible and can decrease the size of primary tumours, enabling optimization of the surgical approach. However, the overall clinical benefit of the neoadjuvant use of toxic drugs, such as axitinib, has not yet been demonstrated.

引用

页码：254 / 255

页数：2

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