A MEMS SENSOR FOR CONTINUOUS MONITORING OF GLUCOSE IN SUBCUTANEOUS TISSUE

被引：0
|
作者：
Huang, X. [1 ]
Li, S. [2 ]
Schultz, J. [3 ]
Wang, Q. [2 ]
Lin, Q. [1 ]
机构：
[1] Columbia Univ, Dept Mech Engn, New York, NY 10027 USA
[2] Univ South Carolina, Chem & Biochem Dept, Columbia, SC USA
[3] Univ Calif, Bioengineering Dept, Riverside, CA USA
来源：
IEEE 22ND INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2009) | 2009年
关键词：
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We present a MEMS sensor for continuous glucose monitoring for diabetes management. The device consists of a microcantilever, which is driven by remote magnetic field and situated in a microchamber separated from the sensing environment by a semi-permeable membrane. As glucose concentration varies, viscosity changes induced by glucose/copolymer binding in a poly(acrylamide-ran-3-acrylamidophenylboronic acid) (PAA-ran-PAAPBA) copolymer solution produce a measurable change in cantilever vibration. The device has been used to measure physiologically relevant glucose concentrations from 0 to 324 mg/dL. The response time of the sensor to glucose concentration changes was 3 minutes and can be further improved with optimized device designs.
引用
收藏
页码：352 / 355
页数：4
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