RACE IT: A prospective, single arm, multicenter, phase II-trial to assess safety and efficacy of preoperative radiation therapy before radical cystectomy combined with immunotherapy in locally advanced urothelial carcinoma of the bladder (AB 65/18)

被引:1
|
作者
Schmid, S. C. [1 ]
Beckert, F. [1 ]
Koll, F. [1 ]
Roedel, C. [2 ]
Seitz, A. K. [3 ]
Maisch, P. [1 ]
Sauter, A. [4 ]
Kuebler, H. [3 ]
Flentje, M. [5 ]
Combs, S. E. [6 ]
Schiller, K. [6 ]
Gschwend, J. [1 ]
Retz, M. [1 ]
机构
[1] TUM Tech Univ Munich, Dept Urol, Rechts Isar Med Ctr, Munich, Germany
[2] Univ Klinikum Frankfurt Johannes Wolfgang Goethe, Radiotherapy, Frankfurt, Germany
[3] Univ Clin Wurzburg, Dept Urol, Wurzburg, Germany
[4] TUM Tech Univ Munich, Dept Radiol, Rechts Isar Med Ctr, Munich, Germany
[5] Univ Clin Wurzburg, Dept Radiat Oncol, Wurzburg, Germany
[6] Tech Univ Muenchen, Dept Radiat Oncol, Klinikum Rechts Isar, Munich, Germany
关键词
D O I
10.1016/j.annonc.2020.08.2068
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
797TiP
引用
收藏
页码:S605 / S605
页数:1
相关论文
共 28 条
  • [1] RACE IT - A prospective, single arm, multicenter, phase II-trial to assess safety and efficacy of preoperative RAdiation therapy before radical CystEctomy combined with ImmunoTherapy in locally advanced urothelial carcinoma of the bladder (AB 65/18)
    Schmid, S. C.
    Schiller, K.
    Seitz, A. K.
    Koll, F. J.
    Beckert, F.
    Korn, P.
    Lewerich, J.
    Maisch, P.
    Sauter, A.
    Roedel, C.
    Flentje, M.
    Riedel, T.
    Combs, S.
    Zengerling, F.
    Bolenz, C.
    Kuebler, H.
    Gschwend, J. E.
    Retz, M.
    EUROPEAN UROLOGY, 2022, 81 : S510 - S510
  • [2] RACE IT: A prospective, single arm, multicenter, phase II-trial to assess safety and efficacy of preoperative RAdiation therapy before radical CystEctomy combined with ImmunoTherapy in locally advanced urothelial carcinoma of the bladder (AB 65/18) - first results
    Schmid, S. C.
    Schiller, K.
    Lewerich, J.
    Seitz, A. K.
    Sauter, A.
    Koll, F.
    Beckert, F.
    Korn, P.
    Maisch, P.
    Roedel, C.
    Flentje, M.
    Wiegel, T.
    Combs, S.
    Zengerling, F.
    Bolenz, C.
    Kuebler, H.
    Gschwend, J.
    Retz, M.
    ANNALS OF ONCOLOGY, 2022, 33 (07) : S1442 - S1442
  • [3] Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer – study protocol of a prospective, single arm, multicenter phase II trial (RACE IT)
    Sebastian C. Schmid
    Florestan J. Koll
    Claus Rödel
    Philipp Maisch
    Andreas Sauter
    Franziska Beckert
    Anna Seitz
    Hubert Kübler
    Michael Flentje
    Felix Chun
    Stephanie E. Combs
    Kilian Schiller
    Jürgen E. Gschwend
    Margitta Retz
    BMC Cancer, 20
  • [4] Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer - study protocol of a prospective, single arm, multicenter phase II trial (RACE IT)
    Schmid, Sebastian C.
    Koll, Florestan J.
    Roedel, Claus
    Maisch, Philipp
    Sauter, Andreas
    Beckert, Franziska
    Seitz, Anna
    Kuebler, Hubert
    Flentje, Michael
    Chun, Felix
    Combs, Stephanie E.
    Schiller, Kilian
    Gschwend, Juergen E.
    Retz, Margitta
    BMC CANCER, 2020, 20 (01)
  • [5] Race IT-Preoperative Radiation Therapy Before Radical Cystectomy Combined with Immunotherapy in Locally Advanced Urothelial Carcinoma of the Bladder
    Beckert, Franziska
    Retz, Margitta
    Lunger, Lukas
    Maisch, Phillip
    Roedel, Claus
    Koll, Florestan
    Sauter, Andreas
    Seitz, Anna
    Kuebler, Hubert
    Flentje, Michael
    Chun, Felix
    Combs, Stephanie
    Schiller, Kilian
    Gschwend, Juergen
    Schmid, Sebastian
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 : 225 - 226
  • [6] Combined Radiation-Immunotherapy in locally advanced Bladder Cancer Prospective, single-arm, multicenter Phase-II Study to evaluate Safety and Efficacy of preoperative Radioimmunotherapy followed by radical Cystectomy in locally advanced Bladder Cancer (RACE-IT) - AB 65/18 of AUO
    Rexer, H.
    Schmid, S.
    Merseburger, A.
    AKTUELLE UROLOGIE, 2020, 51 (02) : 101 - 102
  • [7] RACE IT - A prospective, multicenter, single-arm Phase II Study to Evaluate the Safety and Efficacy of preoperative Radiotherapy in Combination with immunomodulatory Therapy followed by radical Cystectomy in locally advanced Bladder Cancer
    Schiller, K.
    Roedel, C.
    Vogel, M.
    Beckert, F.
    Flentje, M.
    Koll, F. J.
    Maisch, P.
    Sauter, A.
    Seitz, A.
    Kuebler, H.
    Chun, F.
    Combs, S. E.
    Gschwend, J. E.
    Retz, M.
    Schmid, S. C.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2020, 196 (SUPPL 1) : S154 - S154
  • [8] Safety and efficacy of camrelizumab combined with radiotherapy as neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma: a prospective single-arm phase II clinical trial protocol
    Chen, Maohui
    Huang, Yizhou
    Zhang, Shuliang
    Zeng, Taidui
    Huang, Guanglei
    Chen, Chun
    Zheng, Bin
    TRIALS, 2023, 24 (01)
  • [9] Safety and efficacy of camrelizumab combined with radiotherapy as neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma: a prospective single-arm phase II clinical trial protocol
    Maohui Chen
    Yizhou Huang
    Shuliang Zhang
    Taidui Zeng
    Guanglei Huang
    Chun Chen
    Bin Zheng
    Trials, 24 (1)
  • [10] TALASUR trial: a single arm phase II trial assessing efficacy and safety of TALazoparib and Avelumab as maintenance therapy in platinum-Sensitive metastatic or locally advanced URothelial carcinoma
    Elodie Coquan
    Bénédicte Clarisse
    Justine Lequesne
    Pierre-Emmanuel Brachet
    Zoé Nevière
    Emeline Meriaux
    Isabelle Bonnet
    Marie Castera
    Nicolas Goardon
    Jeremy Boutrois
    Romain Travers
    Florence Joly
    Jean-Michel Grellard
    Antoine Thiery-Vuillemin
    BMC Cancer, 22