ADJUVANT REGORAFENIB IN STAGE IV COLORECTAL CANCER (CRC) AFTER CURATIVE TREATMENT OF LIVER METASTASES: A PHASE III RANDOMIZED, PLACEBO-CONTROLLED STUDY (COAST)

被引：0
|
作者：
Eric, Van Cutsem [1 ]
Takayuki, Yoshino [2 ]
Xu Rui-Hua [3 ]
John, Zalcberg [4 ]
Daniel, Sargent [5 ,6 ]
Michael, Choti [7 ]
Mark, Rutstein [8 ]
Lisa, Cupit [8 ]
Iris, Kuss [9 ]
Axel, Grothey [10 ]
机构：
[1] UZ Leuven, Leuven Canc Inst, Leuven, Belgium
[2] Natl Canc Ctr Hosp East, Kashiwa, Chiba, Japan
[3] Sun Yat Sen Univ, Ctr Canc, Guangzhou 510275, Guangdong, Peoples R China
[4] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[5] Mayo Clin, Rochester, MN USA
[6] Mayo Canc Ctr, Rochester, MN USA
[7] UT Southwestern Med Ctr, Dallas, TX USA
[8] Bayer Healthcare, Whippany, NJ USA
[9] Bayer Pharma AG, Berlin, Germany
[10] Mayo Clin, Coll Med, Div Med Oncol, Rochester, MN USA
来源：
ANNALS OF ONCOLOGY | 2014年 / 25卷
关键词：
D O I：
10.1093/annonc/mdu165.261
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P - 0266
引用
收藏
页码：92 / 92
页数：1
相关论文
共 50 条
  • [21] Espindolol for the treatment and prevention of cachexia in patients with stage III/IV non-small cell lung cancer or colorectal cancer: a randomized, double-blind, placebo-controlled, international multicentre phase II study (the ACT-ONE trial)
    Coats, Andrew J. Stewart
    Ho, Gwo Fuang
    Prabhash, Kumar
    von Haehling, Stephan
    Tilson, Julia
    Brown, Richard
    Beadle, John
    Anker, Stefan D.
    JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2016, 7 (03) : 355 - 365
  • [22] A randomized, placebo-controlled, double-blind phase 2 trial of peri-operative cimetidine (CIM) in early colorectal cancer (CRC).
    Jameson, Michael B.
    Findlay, Michael P. N.
    Bissett, Ian
    Lolohea, Simione
    Warren, Judith
    Frizelle, Frank
    Keating, John
    Jacobson, Gregory M.
    Arendse, Michael
    Romano, Claudia
    van Dalen, Ralph
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [23] Final analysis of a randomized placebo-controlled double-blind phase II trial of perioperative cimetidine (CIM) in early colorectal cancer (CRC)
    Jameson, Michael B.
    Arendse, Michael
    Pillai, Avinesh
    Warren, Judith
    Lolohea, Simione
    van Dalen, Ralph
    Frizelle, Frank
    Keating, John
    Romano, Claudia
    Bissett, Ian
    Findlay, Michael P. N.
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [24] A randomized double-blind, placebo-controlled trial of the effect of rofecoxib on proliferation, apoptosis and microvessel density in colorectal cancer liver metastases
    Fenwick, SW
    Toogood, GJ
    Lodge, JPA
    Hull, MA
    BRITISH JOURNAL OF SURGERY, 2003, 90 : 86 - 86
  • [25] RANDOMIZED PHASE II STUDY OF HEPATIC ARTERIAL INFUSION WITH OR WITHOUT ANTINEOPLASTONS AS ADJUVANT THERAPY AFTER HEPATECTOMY FOR LIVER METASTASES FROM COLORECTAL CANCER
    Ogata, Y.
    Shirouzu, K.
    Matono, K.
    Ushijima, M.
    Uchida, S.
    Tsuda, H.
    ANNALS OF ONCOLOGY, 2010, 21 : 221 - 221
  • [26] A randomized, double-blind, placebo-controlled multicenter phase III study comparing denosumab with placebo as adjuvant treatment for women with early-stage breast cancer who are at high risk of disease recurrence (D-CARE).
    Goss, P. E.
    Barrios, C. H.
    Bell, R.
    Finkelstein, D.
    Iwata, H.
    Martin, M.
    Braun, A. H.
    Dansey, R. D.
    Coleman, R. E.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [27] Intravenous amifostine during chemoradiotherapy for head-and-neck cancer: A randomized placebo-controlled phase III study
    Buentzel, J
    Micke, O
    Adamietz, IA
    Monnier, A
    Glatzel, M
    De Vries, A
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 64 (03): : 684 - 691
  • [28] REsect: Blinded assessment of amenability to potentially curative treatment of previously unresectable colorectal cancer liver metastases (CRC LM) after chemotherapy ± RadioEmbolization (SIRT) in the randomized SIRFLOX trial.
    Garlipp, Benjamin
    Gibbs, Peter
    Van Hazel, Guy A.
    Jeyarajah, Rohan
    Martin, Robert C. G.
    Bruns, Christiane J.
    Lang, Hauke
    Manas, Derek M.
    Ettorre, Giuseppe Maria
    Fernando
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [29] ADJUVANT HEPATIC INTRAARTERIAL CHEMOTHERAPY AFTER POTENTIALLY CURATIVE HEPATECTOMY FOR LIVER METASTASES FROM COLORECTAL-CANCER - A PILOT-STUDY
    MORIYA, Y
    SUGIHARA, K
    HOJO, K
    MAKUUCHI, M
    EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 1991, 17 (05): : 519 - 525
  • [30] A randomized phase III, double- blinded, placebo-controlled trial of aspirin as adjuvant therapy for breast cancer (A011502): The Aspirin after Breast Cancer (ABC) Trail
    Chen, Wendy Y.
    Ballman, Karla V.
    Winer, Eric P.
    Openshaw, Thomas H.
    Hahn, Olwen Mary
    Briccetti, Frederick M.
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (36)
12345