MIRD Pamphlet No. 26: Joint EANM/MIRD Guidelines for Quantitative 177Lu SPECT Applied for Dosimetry of Radiopharmaceutical Therapy

被引：223

作者：

Ljungberg, Michael ^{[1
]}

Celler, Anna ^{[2
]}

Konijnenberg, Mark W. ^{[3
]}

Eckerman, Keith F. ^{[4
]}

Dewaraja, Yuni K. ^{[5
]}

Sjogreen-Gleisner, Katarina

Bolch, Wesley E.

Brill, A. Bertrand

Fahey, Frederic

Fisher, Darrell R.

Hobbs, Robert

Howell, Roger W.

Meredith, Ruby F.

Sgouros, George

Zanzonico, Pat

Bacher, Klaus

Chiesa, Carlo

Flux, Glenn

Lassmann, Michael

Strigari, Lidia

Walrand, Stephan

机构：

[1] Lund Univ, Dept Med Radiat Phys, SE-22185 Lund, Sweden

[2] Univ British Columbia, Dept Radiol, Med Imaging Res Grp, Vancouver, BC, Canada

[3] Erasmus Univ, Med Ctr, Dept Nucl Med, Rotterdam, Netherlands

[4] Easterly Sci, Knoxville, TN USA

[5] Univ Michigan, Sch Med, Dept Radiol, Ann Arbor, MI USA

来源：

JOURNAL OF NUCLEAR MEDICINE | 2016年 / 57卷 / 01期

基金：

瑞典研究理事会;

关键词：

image processing; oncology; endocrine; radiobiology/dosimetry; radionuclide therapy; SPECT/CT; guideline; lutetium; quantitative SPECT; RADIOLABELED SOMATOSTATIN ANALOG; RECEPTOR RADIONUCLIDE THERAPY; NEUROENDOCRINE TUMORS; INDIVIDUALIZED DOSIMETRY; 3-DIMENSIONAL DOSIMETRY; ACTIVITY QUANTIFICATION; MONOCLONAL-ANTIBODY; SCATTER CORRECTION; MEMBRANE ANTIGEN; DOSE ASSESSMENT;

D O I：

10.2967/jnumed.115.159012

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The accuracy of absorbed dose calculations in personalized internal radionuclide therapy is directly related to the accuracy of the activity (or activity concentration) estimates obtained at each of the imaging time points. MIRD Pamphlet no. 23 presented a general overview of methods that are required for quantitative SPECT imaging. The present document is next in a series of isotope-specific guidelines and recommendations that follow the general information that was provided in MIRD 23. This paper focuses on Lu-177 (lutetium) and its application in radiopharmaceutical therapy.

引用

页码：151 / 162

页数：12

共 34 条

[31] Scan speed reduction in post-therapy [177Lu]LuPSMA SPECT/CT: How fast can we go without affecting accuracy of dosimetry calculations?
Post, G.
Homan, J. F.
Noordzij, W.
Ivashchenko, O. V.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 : S153 - S153
[32] SPECT/CT Quantification of Lu-177 Activity Using Phantom Images to Develop a Quantitative 3D Dosimetry for Molecular Radionuclide Therapy
Wiessalla, S.
Schuchardt, C.
Baum, R. P.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 : S404 - S404
[33] Investigation of the biodistribution and dosimetry for combined Lu-177/Ac225-PSMA-I&T therapy using multi-isotope quantitative SPECT imaging
Delker, A.
Schleske, M.
Liubchenko, G.
Berg, I.
Zacherl, M. J.
Brendel, M.
Gildehaus, F. J.
Harbach, A.
Rumiantcev, M.
Resch, S.
Kaiser, L.
Brosch-Lenz, J.
Wenter, V.
Unterrainer, L.
Bartenstein, P.
Ziegler, S.
Beyer, L.
Boning, G.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 49 (SUPPL 1) : S126 - S127
[34] Monte Carlo bone marrow dosimetry in radioligand therapy using patient-specific marrow and lesion localization from quantitative 99mTc-sulfur colloid and 177Lu-PSMA-617 SPECT/CT
Peterson, Avery
Wilderman, Scott
Wong, Ka Kit
Frey, Kirk
Dewaraja, Yuni
JOURNAL OF NUCLEAR MEDICINE, 2023, 64

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