Synthesis of a new conjugated polymer for cell membrane imaging by using an intracellular targeting strategy

被引：38
|
作者：
Wang, Bing [1 ]
Zhu, Chunlei [1 ]
Liu, Libing [1 ]
Lv, Fengting [1 ]
Yang, Qiong [1 ]
Wang, Shu [1 ]
机构：
[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Beijing 100190, Peoples R China
来源：
POLYMER CHEMISTRY | 2013年 / 4卷 / 20期
基金：
中国国家自然科学基金;
关键词：
POLYHEDRAL OLIGOMERIC SILSESQUIOXANE; OPTICAL-DETECTION; CHEMICAL SENSORS; DRUG-DELIVERY; CANCER-CELLS; IN-VITRO; NANOPARTICLES; GROWTH; DNA; AMPLIFICATION;
D O I：
10.1039/c3py00097d
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A water soluble polythiophene with tyrosine kinase inhibitor lapatinib as side chain moieties (PTL) was designed and synthesized. Together with its fluorescent characteristic and low cytotoxicity, PTL can be used for cell membrane imaging of living cells by targeting the intracellular domain of transmembrane proteins.
引用
收藏
页码：5212 / 5215
页数：4
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