(1R,3S,5R,6S)-6-Acetoxy-8-methyl-3-(p-tolylsulfonyloxy)-8-azoniabicyclo[3.2.1]octane (2R,3R)-2,3-bis(benzoyloxy)-3-carboxypropanoate

被引：3

作者：

Yang, Li-Min ^{[1
]}

Xie, Yi-Fan ^{[1
]}

Gu, Ya-Fang ^{[1
]}

Chen, Hong-Zhuan ^{[1
]}

Lu, Yang ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Dept Pharm, Sch Med, Shanghai 200025, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷

关键词：

D O I：

10.1107/S1600536809012732

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C17H24NO5S+ center dot C18H13O8-, is the key intermediate during the preparation of lesatropane [systematic name (1R,3S,5R,6S)-6-acetoxy-3-(4-methylphenylsulfonyloxy)tropane], a potential antiglaucoma agent. The tertiary N atom of the tropane ring is involved in intermolecular N-H center dot center dot center dot O hydrogen bonding, and the carboxylate groups are involved in intermolecular O-H center dot center dot center dot O hydrogen bonding.

引用

页码：O1037 / U2158

页数：14

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