(1R,3S,5R,6S)-6-Acetoxy-8-methyl-3-(p-tolylsulfonyloxy)-8-azoniabicyclo[3.2.1]octane (2R,3R)-2,3-bis(benzoyloxy)-3-carboxypropanoate

被引：3
|
作者：
Yang, Li-Min [1 ]
Xie, Yi-Fan [1 ]
Gu, Ya-Fang [1 ]
Chen, Hong-Zhuan [1 ]
Lu, Yang [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Dept Pharm, Sch Med, Shanghai 200025, Peoples R China
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷
关键词：
D O I：
10.1107/S1600536809012732
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C17H24NO5S+ center dot C18H13O8-, is the key intermediate during the preparation of lesatropane [systematic name (1R,3S,5R,6S)-6-acetoxy-3-(4-methylphenylsulfonyloxy)tropane], a potential antiglaucoma agent. The tertiary N atom of the tropane ring is involved in intermolecular N-H center dot center dot center dot O hydrogen bonding, and the carboxylate groups are involved in intermolecular O-H center dot center dot center dot O hydrogen bonding.
引用
收藏
页码：O1037 / U2158
页数：14
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