Oxygen transport and utilisation during exercise in cystic fibrosis: contributors to exercise intolerance

被引:5
|
作者
Saynor, Zoe L. [1 ]
Gruet, Mathieu [2 ]
Rodriguez-Miguelez, Paula [3 ]
Harris, Ryan A. [4 ]
机构
[1] Univ Portsmouth, Fac Sci & Hlth, Sch Sport Hlth & Exercise Sci, Portsmouth PO12ER, Hants, England
[2] Toulon Univ, Lab Impact Phys Act Hlth IAPS, Toulon, France
[3] Virginia Commonwealth Univ, Coll Humanities & Sci, Dept Kinesiol & Hlth Sci, Richmond, VA USA
[4] Augusta Univ, Dept Med, Georgia Prevent Inst, Augusta, GA USA
关键词
cystic fibrosis; exercise intolerance; haemodynamics; O-2; delivery; utilisation; TRANSMEMBRANE CONDUCTANCE REGULATOR; CHLORIDE CHANNEL; HEART INVOLVEMENT; UPTAKE KINETICS; YOUNG-PATIENTS; DYSFUNCTION; SILDENAFIL; ADULTS;
D O I
10.1113/EP088106
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
New Findings What is the topic of this review? This review highlights the central and peripheral mechanisms that alter oxygen transport and utilisation and thereby contribute to exercise limitation in people with cystic fibrosis, considering also viable therapeutic targets for intervention.
引用
收藏
页码:1979 / 1983
页数:5
相关论文
共 50 条
  • [21] EXERCISE AND CYSTIC-FIBROSIS
    WEBB, AK
    DODD, ME
    MOORCROFT, J
    [J]. JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 1995, 88 : 30 - 36
  • [22] OXYGEN EXTRACTION DURING EXERCISE IN PATIENTS WITH CYSTIC FIBROSIS: THE ROLE OF HBA1C
    Quertermous, B. P.
    Seigler, N.
    Loone, J.
    Crandall, R.
    Blackburn, M.
    Bubb, A.
    Blanks, A.
    Harris, R. A.
    [J]. PEDIATRIC PULMONOLOGY, 2020, 55 : S83 - S83
  • [23] Predictability of oxygen desaturation during sleep in patients with cystic fibrosis - Clinical, spirometric, and exercise parameters
    Frangolias, DD
    Wilcox, PG
    [J]. CHEST, 2001, 119 (02) : 434 - 441
  • [24] Diffusing capacity for carbon monoxide (TLCO) and oxygen saturation during exercise in patients with cystic fibrosis
    Chemery, L
    Fekete, K
    Guillot, S
    Roussey, M
    Desrues, B
    Dabadie, A
    Belleguic, C
    Deneuville, E
    Dassonville, J
    [J]. ARCHIVES DE PEDIATRIE, 2004, 11 (09): : 1060 - 1066
  • [25] Sleep disorders are distinctively associated with exercise intolerance and sedentary behavior in children with cystic fibrosis
    Barbosa, Roberta Ribeiro Batista
    Coelho, Pitiguara de Freitas
    Liberato, Fernanda Mayrink Goncalves
    Vidal, Pamela dos Reis
    Couto Olimpio de Carvalho, Roberta Barcellos
    Nunes Cruz Melotti, Roberta de Cassia
    Donadio, Marcio Vinicius Fagundes
    [J]. SLEEP MEDICINE, 2020, 74 : 145 - 151
  • [26] Oxygen pressure measurement during grip exercise reveals exercise intolerance after radial harvest
    Manabe, S
    Tabuchi, N
    Toyama, M
    Yoshizaki, T
    Kato, M
    Wu, HS
    Kotani, M
    Sunamori, M
    [J]. ANNALS OF THORACIC SURGERY, 2004, 77 (06): : 2066 - 2070
  • [27] Effect of supplemental oxygen on supramaximal exercise performance and recovery in cystic fibrosis
    Shah, AR
    Keens, TG
    Gozal, D
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1997, 83 (05) : 1641 - 1647
  • [28] Exercise-induced changes of oxygen saturation in patients with cystic fibrosis
    Stern, M
    Strauss, H
    [J]. MONATSSCHRIFT KINDERHEILKUNDE, 1996, 144 (09) : 910 - 917
  • [29] The effects of supplemental oxygen on submaximal exercise in patients with cystic fibrosis.
    McKone, EF
    Barry, SC
    FitzGerald, MX
    Gallagher, CG
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) : A414 - A414
  • [30] DYNAMIC HYPERINFLATION DURING CARDIOPULMONARY EXERCISE TESTING IN CYSTIC FIBROSIS
    Stevens, D.
    Stephenson, A.
    Faughnan, M. E.
    Leek, E.
    Tullis, E.
    [J]. PEDIATRIC PULMONOLOGY, 2012, 47 : 369 - 370