THE CYSTEINE PROTEASE CATHEPSIN B IS A KEY DRUG TARGET AND CYSTEINE PROTEASE INHIBITORS ARE POTENTIAL THERAPEUTICS FOR TBI

被引：0
|
作者：
Hook, G. R. [1 ]
Yu, J. [2 ,3 ]
Sipes, N. [1 ]
Pierschbacher, M. D. [1 ]
Hook, V [4 ]
Kindy, M. S. [2 ,3 ]
机构：
[1] Amer Life Sci Pharmaceut, La Jolla, CA USA
[2] Med Univ S Carolina, Charleston, SC USA
[3] Appl Neurotechnol Inc, Charleston, SC USA
[4] Univ Calif San Diego, La Jolla, CA 92093 USA
来源：
JOURNAL OF NEUROTRAUMA | 2014年 / 31卷 / 12期
关键词：
cathepsin B; drug; target; TBI;
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
C2-34
引用
收藏
页码：A88 / A88
页数：1
相关论文
共 50 条
  • [1] The Cysteine Protease Cathepsin B Is a Key Drug Target and Cysteine Protease Inhibitors Are Potential Therapeutics for Traumatic Brain Injury
    Hook, Gregory R.
    Yu, Jin
    Sipes, Nancy
    Pierschbacher, Michael D.
    Hook, Vivian
    Kindy, Mark S.
    JOURNAL OF NEUROTRAUMA, 2014, 31 (05) : 515 - 529
  • [2] Differential localization of cysteine protease inhibitors and a target cysteine protease, cathepsin B, by immuno-confocal microscopy
    Calkins, CC
    Sameni, M
    Koblinski, J
    Sloane, BF
    Moin, K
    JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1998, 46 (06) : 745 - 751
  • [3] The cysteine protease cathepsin B in cancer
    Elliott, E
    Sloane, BF
    PERSPECTIVES IN DRUG DISCOVERY AND DESIGN, 1996, 6 : 12 - 32
  • [4] CATHEPSIN-B AND CYSTEINE PROTEASE INHIBITORS IN HUMAN OSTEOARTHRITIS
    MARTELPELLETIER, J
    CLOUTIER, JM
    PELLETIER, JP
    JOURNAL OF ORTHOPAEDIC RESEARCH, 1990, 8 (03) : 336 - 344
  • [5] Nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S
    Thurmond, RL
    Beavers, MP
    Cai, H
    Meduna, SP
    Gustin, DJ
    Sun, SQ
    Almond, HJ
    Karlsson, L
    Edwards, JP
    JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (20) : 4799 - 4801
  • [6] In Search of Selective Inhibitors of Cysteine Protease, Cathepsin K
    Ewa Wieczerzak
    Piotr Drabik
    Magnus Abrahamson
    Anders Grubb
    International Journal of Peptide Research and Therapeutics, 2005, 11 : 203 - 209
  • [7] In search of selective inhibitors of cysteine protease, cathepsin K
    Wieczerzak, E
    Drabik, P
    Abrahamson, M
    Grubb, A
    INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2005, 11 (03) : 203 - 209
  • [8] Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K
    Marquis, RW
    Ru, Y
    Yamashita, DS
    Oh, HJ
    Yen, J
    Thompson, SK
    Carr, TJ
    Levy, MA
    Tomaszek, TA
    Ijames, CF
    Smith, WW
    Zhao, BG
    Janson, CA
    Abdel-Meguid, SS
    D'Alessio, KJ
    McQueney, MS
    Veber, DF
    BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (04) : 581 - 588
  • [9] Cyclic ketone inhibitors of the cysteine protease cathepsin K
    Marquis, RW
    Ru, Y
    Zeng, J
    Trout, REL
    LoCastro, SM
    Gribble, AD
    Witherington, J
    Fenwick, AE
    Garnier, B
    Tomaszek, T
    Tew, D
    Hemling, ME
    Quinn, CJ
    Smith, WW
    Zhao, BG
    McQueney, MS
    Janson, CA
    D'Alessio, K
    Veber, DF
    JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (05) : 725 - 736
  • [10] Cysteine protease cathepsin S as a key step in antigen presentation
    Liu, WM
    Spero, DM
    DRUG NEWS & PERSPECTIVES, 2004, 17 (06) : 357 - 363
12345