Humanized immune system mouse models: progress, challenges and opportunities

被引:147
|
作者
Allen, Todd M. [1 ]
Brehm, Michael A. [2 ]
Bridges, Sandra [3 ]
Ferguson, Stacy [4 ]
Kumar, Priti [5 ]
Mirochnitchenko, Oleg [6 ]
Palucka, Karolina [7 ]
Pelanda, Roberta [8 ]
Sanders-Beer, Brigitte [3 ]
Shultz, Leonard D. [9 ]
Su, Lishan [10 ]
PrabhuDas, Mercy [4 ]
机构
[1] Ragon Inst MGH MIT & Harvard, Cambridge, MA USA
[2] Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA USA
[3] NIAID, Div AIDS, NIH, Rockville, MD USA
[4] NIAID, Div Allergy Immunol & Transplantat, NIH, Rockville, MD 20852 USA
[5] Yale Sch Med, Dept Internal Med, Infect Dis Sect, New Haven, CT USA
[6] NIH, Off Res Infrastruct Programs, Div Program Coordinat Planning & Strateg Initiat, Off Director, Bldg 10, Bethesda, MD 20892 USA
[7] Jackson Lab, Farmington, CT USA
[8] Univ Colorado, Dept Immunol & Microbiol, Aurora, CO USA
[9] Jackson Lab, 600 Main St, Bar Harbor, ME 04609 USA
[10] Univ N Carolina, Chapel Hill, NC 27515 USA
关键词
MICE; INFECTION; CELLS;
D O I
10.1038/s41590-019-0416-z
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
On 18 December 2018, the National Institute of Allergy and Infectious Diseases convened a workshop entitled ‘Recent Advances and Opportunities in the Development and Use of Humanized Immune System Mouse Models’.
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页码:770 / 774
页数:5
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