3D microstructuring of smart bioactive hydrogels based on recombinant elastin-like polymers

被引:23
|
作者
Martin, Laura [1 ]
Alonso, Matilde [1 ]
Moeller, Martin [2 ,3 ]
Rodriguez-Cabello, Jose Carlos [1 ]
Mela, Petra [2 ,3 ]
机构
[1] Univ Valladolid, GIR Bioforge, E-47011 Valladolid, Spain
[2] Rhein Westfal TH Aachen, Inst Tech & Macromol Chem, D-52056 Aachen, Germany
[3] DWI eV, D-52056 Aachen, Germany
关键词
MATRIX;
D O I
10.1039/b823488d
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We describe a simple method of replica moulding to obtain novel 3D microstructured smart hydrogels based on protein polymers mimicking the structure and behaviour of the extracellular matrix (ECM).
引用
收藏
页码:1591 / 1593
页数:3
相关论文
共 50 条
  • [21] Tunable Elastin-Like Protein (Elp)-Based Hydrogels for Cell Transplantation in Vascular Repair
    Shayan, Mahdis
    Navarro, Renato S.
    Huang, Michelle
    Heilshorn, Sarah C.
    Huang, Ngan F.
    CIRCULATION, 2022, 146
  • [22] Hybrid Elastin-like Polypeptide-Polyethylene Glycol Hydrogels for 3D Cell Culture with Tunable Matrix Stiffness and Cell Ligand Density
    Wang, H.
    Cai, L.
    Paul, A.
    Enejder, A.
    Heilshorn, S. C.
    TISSUE ENGINEERING PART A, 2015, 21 : S308 - S309
  • [23] Regeneration of hyaline cartilage promoted by xenogeneic mesenchymal stromal cells embedded within elastin-like recombinamer-based bioactive hydrogels
    Pescador, David
    Ibanez-Fonseca, Arturo
    Sanchez-Guijo, Fermin
    Brinon, Jesus G.
    Javier Arias, Francisco
    Muntion, Sandra
    Hernandez, Cristina
    Girotti, Alessandra
    Alonso, Matilde
    Consuelo del Canizo, Maria
    Carlos Rodriguez-Cabello, Jose
    Francisco Blanco, Juan
    JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2017, 28 (08)
  • [24] Genetically engineered elastin-like recombinamers with sequence-based molecular stabilization as advanced bioinks for 3D bioprinting
    Salinas-Fernandez, Soraya
    Santos, Mercedes
    Alonso, Matilde
    Quintanilla, Luis
    Carlos Rodriguez-Cabello, Jose
    APPLIED MATERIALS TODAY, 2020, 18
  • [25] Elastin-Like Recombinamers: Deconstructing and Recapitulating the Functionality of Extracellular Matrix Proteins Using Recombinant Protein Polymers
    Acosta, Sergio
    Quintanilla-Sierra, Luis
    Mbundi, Lubinda
    Reboto, Virginia
    Carlos Rodriguez-Cabello, Jose
    ADVANCED FUNCTIONAL MATERIALS, 2020, 30 (44)
  • [26] Regeneration of hyaline cartilage promoted by xenogeneic mesenchymal stromal cells embedded within elastin-like recombinamer-based bioactive hydrogels
    David Pescador
    Arturo Ibáñez-Fonseca
    Fermín Sánchez-Guijo
    Jesús G. Briñón
    Francisco Javier Arias
    Sandra Muntión
    Cristina Hernández
    Alessandra Girotti
    Matilde Alonso
    María Consuelo del Cañizo
    José Carlos Rodríguez-Cabello
    Juan Francisco Blanco
    Journal of Materials Science: Materials in Medicine, 2017, 28
  • [27] Elastin-like polypeptides as a promising family of genetically-engineered protein based polymers
    Tomasz Kowalczyk
    Katarzyna Hnatuszko-Konka
    Aneta Gerszberg
    Andrzej K. Kononowicz
    World Journal of Microbiology and Biotechnology, 2014, 30 : 2141 - 2152
  • [28] A Library of Elastin-like Proteins with Tunable Matrix Ligands for In Vitro 3D Neural Cell Culture
    Suhar, Riley A.
    Huang, Michelle S.
    Navarro, Renato S.
    Aviles Rodriguez, Giselle
    Heilshorn, Sarah C.
    BIOMACROMOLECULES, 2023, 24 (12) : 5926 - 5939
  • [29] Elastin-like polypeptides as a promising family of genetically-engineered protein based polymers
    Kowalczyk, Tomasz
    Hnatuszko-Konka, Katarzyna
    Gerszberg, Aneta
    Kononowicz, Andrzej K.
    WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2014, 30 (08): : 2141 - 2152
  • [30] Octa-arginine boosts the penetration of elastin-like polypeptide nanoparticles in 3D cancer models
    van Oppen, Lisanne M. P. E.
    Pille, Jan
    Stuut, Christiaan
    van Stevendaal, Marleen
    van der Vorm, Lisa N.
    Smeitink, Jan A. M.
    Koopman, Werner J. H.
    Willems, Peter H. G. M.
    van Hest, Jan C. M.
    Brock, Roland
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2019, 137 : 175 - 184