Responsive DNA-Based Supramolecular Hydrogels

被引:50
|
作者
Shi, Jiezhong [1 ]
Shi, Ziwei [2 ]
Dong, Yuanchen [2 ]
Wu, Fen [3 ]
Liu, Dongsheng [1 ]
机构
[1] Tsinghua Univ, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Dept Chem, Beijing 100084, Peoples R China
[2] Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
[3] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China
基金
中国国家自然科学基金;
关键词
DNA hydrogels; stimuli responsiveness; biomedical applications; supramolecular interactions; DNA nanoteclznology; RATIONAL DESIGN; APTAMER; RELEASE; NANOTECHNOLOGY; HYBRIDIZATION; EXCHANGE; DUPLEX;
D O I
10.1021/acsabm.0c00081
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
DNA supramolecular hydrogels are hydrogels cross-linked through DNA hybridization. They have attracted wide attention due to their great molecular permeability, biocompatibility, degradability, thixotropy, and self-healing properties, which make them very useful in cell culture, tissue engineering, and 3D printing. The designability and responsiveness of DNA endows these hydrogels with specific stimuli responsiveness, thus enhancing their utility for more applications, e.g., detection devices and shape-memory materials. In this review, we outlined and discussed the development of responsive DNA supramolecular hydrogels, and their applications have also been summarized.
引用
收藏
页码:2827 / 2837
页数:11
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