Does diet affect breast cancer risk?

被引：50

作者：

Holmes, MD ^{[1
]}

Willett, WC

机构：

[1] Harvard Univ, Sch Med, Dept Med, Channing Lab, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Boston, MA 02115 USA

[3] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA

[4] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

来源：

BREAST CANCER RESEARCH | 2004年 / 6卷 / 04期

关键词：

breast neoplasms; diet; ethanol; obesity; women;

D O I：

10.1186/bcr909

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The role of specific dietary factors in breast cancer causation is not completely resolved. Results from prospective studies do not support the concept that fat intake in middle life has a major relation to breast cancer risk. However, weight gain in middle life contributes substantially to breast cancer risk. Alcohol is the best established dietary risk factor, probably by increasing endogenous estrogen levels. Hypotheses relating diet during youth to risk decades later will be difficult to test. Nevertheless, available evidence is strong that breast cancer risk can be reduced by avoiding weight gain during adult years, and by limiting alcohol consumption.

引用

页码：170 / 178

页数：9

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