Understanding the puzzle of 'well-characterized biotechnology products'

被引：2
|
作者：
Sadick, M [1 ]
机构：
[1] Eli Lilly & Co, Bioprod Pharmaceut Dev, Indianapolis, IN 46285 USA
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2002年 / 13卷 / 03期
关键词：
D O I：
10.1016/S0958-1669(02)00320-8
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The concept of a 'well-characterized biotechnology product' is akin to assembling a jigsaw puzzle. Each of the analytical pieces must be assembled to provide a clearly, orthogonally defined picture that addresses completely the physicochemical, biological and pharmacological attributes that fully characterize the molecule.
引用
收藏
页码：275 / 278
页数：4
相关论文
共 50 条
  • [41] Generating well-characterized chemical plumes for remote sensing research
    Chaffin, CT
    Marshall, TL
    ELECTRO-OPTICAL TECHNOLOGY FOR REMOTE CHEMICAL DETECTION AND IDENTIFICATION III, 1998, 3383 : 113 - 123
  • [42] Towards near perfect crystals with only well-characterized imperfections
    Peiser, HS
    JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, 2001, 106 (06): : 1135 - 1139
  • [43] Screening for Well-Characterized Paraneoplastic Antineuronal Antibodies in Multiple Sclerosis
    Stich, Oliver
    Murek, Constanze
    Rasiah, Christiane
    Rauer, Sebastian
    INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2011, 121 (08) : 477 - 479
  • [44] Signal Detection in Clutter and Noise Using Well-Characterized Subspace
    Tang, Hui
    Wan, Xianrong
    Ke, Hengyu
    IEEE SIGNAL PROCESSING LETTERS, 2017, 24 (09) : 1343 - 1347
  • [45] Interaction of well-characterized, longitudinal acoustic waves with a nonreacting spray
    McQuay, M.Q.
    Dubey, R.K.
    Atomization and Sprays: Journal of the International Institutions for Liquid Atomization and Spray Systems, 1998, 8 (04): : 419 - 437
  • [46] Socioeconomic evaluation of well-characterized allergy to staple foods in adults
    Jansson, S. -A.
    Protudjer, J. L. P.
    Heibert, M. Arnlind
    Bengtsson, U.
    Kallstrom-Bengtsson, I.
    Marklund, B.
    Middelveld, R. J. M.
    Rentzos, G.
    Sundqvist, A. C.
    Akerstrom, J.
    Ostblom, E.
    Dahlen, S. -E.
    Ahlstedt, S.
    ALLERGY, 2014, 69 (09) : 1241 - 1247
  • [47] Application of new analytical technology to the production of a "well-characterized biological"
    Apffel, A
    Chakel, J
    Udiavar, S
    Swedberg, S
    Hancock, WS
    Souders, C
    Pungor, E
    CHARACTERIZATION OF BIOTECHNOLOGY PHARMACEUTICAL PRODUCTS, 1998, 96 : 11 - 25
  • [48] Rhamnolipids: Well-Characterized Glycolipids with Potential Broad Applicability as Biosurfactants
    Irfan-Maqsood, Muhammad
    Seddiq-Shams, Mahsa
    Industrial Biotechnology, 2014, 10 (04) : 285 - 291
  • [49] DICYCLOPENTADIENE POLYMERIZATION USING WELL-CHARACTERIZED TUNGSTEN PHENOXIDE COMPLEXES
    BELL, A
    ACS SYMPOSIUM SERIES, 1992, 496 : 121 - 133
  • [50] Unexpected photosensitivity of the well-characterized heme enzyme chlorite dismutase
    Durga Mahor
    Julia Püschmann
    Diederik R. Adema
    Marc J. F. Strampraad
    Peter-Leon Hagedoorn
    JBIC Journal of Biological Inorganic Chemistry, 2020, 25 : 1129 - 1138
12345