Iodine-Catalyzed Regioselective Sulfenylation of Indoles with Sodium Sulfinates

被引：248
|
作者：
Xiao, Fuhong [1 ]
Xie, Hao [1 ]
Liu, Saiwen [1 ]
Deng, Guo-Jun [1 ,2 ]
机构：
[1] Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environm Friendly Chem & Applicat, Xiangtan 411105, Peoples R China
[2] Chinese Acad Sci, Inst Chem, Key Lab Mol Recognit & Funct, Beijing 100080, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 2-3期
基金：
中国国家自然科学基金;
关键词：
indoles; iodine; sodium sulfinates; sulfenylation; transition metal-free conditions; DIRECT ESI-MS; C-H BOND; DIARYL DISULFIDES; ARYL KETONES; THIOLATION; ACIDS; 3-SULFENYLATION; ARYLATION; CHLORIDES; TRIMETHOXYBENZENE;
D O I：
10.1002/adsc.201300773
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An iodine-catalyzed sulfenylation of free indoles with sodium sulfinates is described. The reaction selectively afforded 3-arylthioindoles in good to high yields in anisole under metal-free conditions. Functional groups such as halogens were well tolerated under the optimized reaction conditions.
引用
收藏
页码：364 / 368
页数：5
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