Comparative study of UV spectrophotometric methods for the determination of ethamsylate in bulk and pharmaceutical formulations

被引：0
|
作者：
Rao, RN [1 ]
Nagaraju, P [1 ]
Srinivasulu, C [1 ]
Kumar, PJ [1 ]
Suresh, V [1 ]
Sireesha, D [1 ]
机构：
[1] Coll Pharmaceut Sci, Dept Pharmaceut Chem, Disst Ganjam 760002, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2004年 / 16卷 / 3-4期
关键词：
UV spectrophotometric methods; ethamsylate;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two simple, sensitive and reproducible UV spectrophotometric methods (A and B) for the determination of ethamsylate (EMS) in bulk samples and pharmaceutical formulations are described. EMS was taken in methanol for method A and in 0.1 N HCI for method B. The maximum absorbance was observed at 302 nm for method A and 302 nm for method B. Regression analysis of Beer's law plots showed good concentration ranges 2-10 mug/ml, for method A and 5-15 mug/mL for method B respectively. There is no interference from any common pharmaceutical excipients.
引用
收藏
页码：1956 / 1958
页数：3
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